Computational and structural biology

From the Journals: JBC
How cells recover from stress. Cancer cells need cysteine to proliferate. Method to make small membrane proteins. Read about papers on these topics recently published in the Journal of Biological Chemistry.

Sweet secrets of sperm glycosylation
Scientists from Utrecht University uncover similar glycosylation patterns in sperm from bulls, boars and humans, distinct from those found in blood across species. These findings may improve IVF and farming techniques.

Institute launches a new AI initiative to power biological research
Stowers investigator Julia Zeitlinger selected to head effort and leverage cutting-edge computational techniques to accelerate scientific discoveries.

Computational biosciences illuminate how molecular condensates form
Rohit Pappu will receive the 2025 DeLano Award for Computational Biosciences at the ASBMB Annual Meeting, April 12-15 in Chicago.

3D shapes of viral proteins point to previously unknown roles
A research team led by Jennifer Doudna has harnessed computational and deep-learning tools to predict the shapes of nearly 4,500 species that infect animals and humans.

Nobel for ‘breakthrough in biochemistry’
David Baker, Demis Hassabis and John M. Jumper received the chemistry prize for computational protein design and structure prediction.

Why AlphaFold 3 needs to be open source
The powerful AI-driven software from DeepMind was released without making its code openly available to scientists.

New class of antimicrobials discovered in soil bacteria
Scientists have mined Streptomyces for antibiotics for nearly a century, but the newly identified umbrella toxin escaped notice.

Hinton lab maps structure of mitochondria at different life stages
An international team determines the differences in the 3D morphology of mitochondria and cristae, their inner membrane folds, in brown adipose tissue.