Computational and structural biology
Computational and biophysical approaches to disordered proteins
Rohit Pappu will receive the 2025 DeLano Award for Computational Biosciences at the ASBMB Annual Meeting, April 12-15 in Chicago.
3D shapes of viral proteins point to previously unknown roles
A research team led by Jennifer Doudna has harnessed computational and deep-learning tools to predict the shapes of nearly 4,500 species that infect animals and humans.
Nobel for ‘breakthrough in biochemistry’
David Baker, Demis Hassabis and John M. Jumper received the chemistry prize for computational protein design and structure prediction.
Why AlphaFold 3 needs to be open source
The powerful AI-driven software from DeepMind was released without making its code openly available to scientists.
New class of antimicrobials discovered in soil bacteria
Scientists have mined Streptomyces for antibiotics for nearly a century, but the newly identified umbrella toxin escaped notice.
Hinton lab maps structure of mitochondria at different life stages
An international team determines the differences in the 3D morphology of mitochondria and cristae, their inner membrane folds, in brown adipose tissue.
From the journals: MCP
Three views of mass spec: analyzing secreted protein spectra, imaging mass spectrometry for clinical use and spectral libraries for MS data analysis. Read about these recent papers.
From the journals: MCP
Amino acids and sulfate signatures. Unveiling phosphatase substrates. Simplifying bacterial proteome profiling. Read about recent papers on these topics.
From the journals: JBC
Cap-snatching viruses. Membrane makeup facilitates fusion. A disordered region promotes scaffold activity. Read about recent papers on these topics.