MCP News

Sweet secrets of sperm glycosylation
Scientists from Utrecht University uncover similar glycosylation patterns in sperm from bulls, boars and humans, distinct from those found in blood across species. These findings may improve IVF and farming techniques.

New mass spectrometry assay speeds up UTI diagnosis
Scientists in Quebec use liquid chromatography–mass spectrometry to reduce the time needed to test for bacteria in urine from days to minutes — and with smaller samples.

From the journals: MCP
Protein analysis of dopaminergic neurons. Predicting immunotherapy responses in lung cancer. ZASP: An efficient proteomics sample prep method. Read about papers on these topics recently published in Molecular & Cellular Proteomics.

A proteomic hunt for phosphosites in the aging brain
In older mice, researchers found more enzymes that phosphorylate other proteins and changes in phosphorylation levels in proteins associated with neurodegeneration.

Of yeasts and men: One-hour proteomes, 10 years apart
To profile the human proteome within an hour, the researchers used a new mass spectrometer and packed their liquid chromatography columns with very high pressure.

From the Journals: MCP
Rapid and precise SARS-CoV-2 detection using mass spec. Mapping brain changes from drug addiction. Decoding plant osmotic stress response. Read about recent MCP papers on these topics.

Quantifying how proteins in microbe and host interact
“To develop better vaccines, we need new methods and a better understanding of the antibody responses that develop in immune individuals,” author Johan Malmström said.

From the journals: MCP
Young proteins are more likely to be degraded. Full automation speeds up sample preparation. Proteomics sheds light on cancer immune suppression. Read about recent MCP papers on these topics.

‘We’re thankful for our reviewers’
Meet some of the scientists who review manuscripts for the Journal of Biological Chemistry, Journal of Lipid Research and Molecular & Cellular Proteomics.