Disease mechanisms and treatments

Biotech startup worms its way into therapeutics

Andrea Choe's company, Holoclara, has created an anti-inflammatory drug based on a molecule from worms.

Tiny laboratories that fit in your hand can rapidly identify pathogens using electricity

Pathogens have distinct electrical charges, shapes and sizes. Measuring how quickly they move through an electric field can help researchers separate different species in a sample.

Ubiquitination by TRIM13: An ingredient contributing to diet-induced atherosclerosis

Researchers help unravel the molecular mechanism behind plaque formation in cardiovascular disease.

Predicting fatty liver disease from a tiny blood sample

Obesity and being overweight aren't the only factors that contribute to liver disease. New tests can help identify who is at risk or already has the disease, even in people who are lean or have a normal weight.

From the journals: JLR

Fixation method to quantify brain metabolites. Belly fat and liver disease crosstalk. Stopping heart diseases in schizophrenic patients. Read about the recent JLR papers on these topics.

UCLA researchers engineer experimental drug for preventing heart failure after heart attacks

This new single-dose therapy blocks a protein that increases inflammation and shows promise in enhancing muscle repair in preclinical models.

Helping mitochondria run smoothly may protect against Parkinson’s disease

As the powerhouse of the cell, mitochondria lie at the intersection of many essential biochemical pathways. When they go awry, neurodegenerative diseases can result.

A common parasite could one day deliver drugs to the brain

Bill Sullivan explains how scientists are turning Toxoplasma gondii, often found in contaminated food or cat feces, from foe into friend.

At the Salton Sea, uncovering the culprit of lung disease

Scientists have long suspected a link between the dust and poor respiratory health. According to recent findings, the prime suspect is a naturally occurring toxin.