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Becoming a scientific honey bee
At the World Science Forum, a speaker’s call for scientists to go out and “make honey” felt like the answer to a question Katy Brewer had been considering for a long time.
Mutant RNA exosome protein linked to neurodevelopmental defects
Researchers at Emory University find that a missense mutation impairs RNA exosome assembly and translation and causes neurological disease.
Study sheds light on treatment for rare genetic disorder
Aaron Hoskins’ lab partnered with a drug company to understand how RNA-targeting drugs work on spinal muscular atrophy, a disorder resulting from errors in production of a protein related to muscle movement.
Examining mechanisms of protein complex at a basic cell biological level
Mary Munson is co-corresponding author on a study revealing functions and mechanisms of the exocyst that are essential to how molecules move across a membrane through vesicles in a cell.
Breaking through limits in kinase inhibition
Paul Shapiro, the first speaker on ASBMB Breakthroughs, a new webinar series highlighting research from ASBMB journals, discussed taking ideas and discoveries from basic science research toward clinical applications.
How opposing metabolic pathways regulate inflammation
Researchers use cybernetics to understand what happens when two acids produced by macrophages compete for binding sites on the enzyme that converts them to active products.
We are all mosaics
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From the journals: MCP
Finding biomarkers for preeclampsia. Early diagnostic biomarkers of pancreatic cancer. Better tools to identify tumor-specific peptides. Read about these recent MCP papers.
RNA binding proteins with benefits
Blanton Tolbert studies the biochemical mechanisms of RNA virus replication while working to make science more accessible, and more interesting, for all people.
A proteomic hunt for phosphosites in the aging brain
In older mice, researchers found more enzymes that phosphorylate other proteins and changes in phosphorylation levels in proteins associated with neurodegeneration.
What if a virus could reverse antibiotic resistance?
In promising experiments, phage therapy forces bacteria into a no-win dilemma that lowers their defenses against drugs they’d evolved to withstand.
Tapping into bacterial conversations
Bonnie Bassler has helped usher in a new branch of science centered on quorum sensing, the process by which bacteria communicate with one another and orchestrate collective tasks.
From the journals: JLR
Can diacylglycerol combat athlete hyperuricemia? Inhibiting a cardiac enzyme improves metabolism. Targeting angiopoietins to combat liver injury. Read about papers on these topics recently published in the Journal of Lipid Research.
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