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Phosphatases and pupils: A dual legacy
Yale professor Anton Bennett explores how protein tyrosine phosphatases shape disease, while building a legacy of mentorship that expands opportunity and fuels discovery in biochemistry and molecular biology.
Extracellular vesicles offer clues to cattle reproduction
Extracellular vesicles from pregnant cattle support embryo development better than laboratory models, highlighting their potential to improve reproductive efficiency in bovine embryo cultures. Read more about this recent MCP paper.
Proteomics reveals protein shifts in diabetic eye disease
Using proteomics, researchers identified protein changes in eye fluid that mark diabetic retinopathy progression and may serve as biomarkers for vision-threatening complications. Read more about this recent MCP paper.
Protein modifications drive lung cancer resistance
New assay enriches protein modifications in a single process, enabling detection of key changes in drug-resistant lung cancer cells that may guide future therapies.
How antigen-processing proteins shape immunity
Researchers show how components of the antigen processing machinery shape the immunopeptidome, offering insights into immune regulation and cancer biology.
New chemical strategy boosts accuracy in proteomics
Researchers develop a methylamine-based method that nearly eliminates peptide overlabeling in proteomics, improving accuracy in protein identification and quantitation.
Understanding the roles of extracellular matrix and vesicles in valvular disease
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Lipid profiles reveal sex differences in type 2 diabetes
Researchers explored the lipid profiles of individuals with type 2 diabetes and identified potentially useful lipid biomarkers for this condition.
Serum lipids may predict early diabetes risk
Researchers found that levels of two key fatty acids may predict worsening tolerance for glucose, independent of body fat and insulin levels. In turn, these fatty acids may serve as early T2D biomarkers.
Sex and diet shape fat tissue lipid profiles in obesity
Researchers found that sex hormone levels and diet both influence inflammation and lipid composition in obesity.
Mapping the placenta’s hormone network
Study uncovers how the placenta actively metabolizes not only glucocorticoids but also novel androgens and progesterones, reshaping our understanding of pregnancy and its complications.
Biochemists and molecular biologists sweep major 2025 honors
Recent Nobel, MacArthur and Kimberly Prize honorees highlight the power of biochemistry and molecular biology to drive discovery, including immune tolerance, vaccine design and metabolic disease, and to advance medicine and improve human health.
Spider-like proteins spin defenses to control immunity
Researchers from Utrecht University discovered two distinct binding modes of a spider-shaped immune inhibitor found in serum.
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