Proteins and proteomics

From the Journals: JBC

How cells recover from stress. Cancer cells need cysteine to proliferate. Method to make small membrane proteins. Read about papers on these topics recently published in the Journal of Biological Chemistry.

ASBMB names 2025 JBC/Tabor Award winners

The six awardees are first authors of outstanding papers published in 2024 in the Journal of Biological Chemistry.

Pan-kinase inhibitor for head and neck cancer enters clinical trials

A drug targeting the scaffolding function of multiple related kinases halts tumor progression.

Sweet secrets of sperm glycosylation

Scientists from Utrecht University uncover similar glycosylation patterns in sperm from bulls, boars and humans, distinct from those found in blood across species. These findings may improve IVF and farming techniques.

From the Journals: MCP

Protein acetylation helps plants adapt to light. Mapping protein locations in 3D tissues. Demystifying the glycan–protein interactome. Read about these recent papers.

From the journals: MCP

Protein analysis of dopaminergic neurons. Predicting immunotherapy responses in lung cancer. ZASP: An efficient proteomics sample prep method. Read about papers on these topics recently published in Molecular & Cellular Proteomics.

Ten interesting quotes from the JBC archives

Older papers include archaic quirks and long-abandoned biological concepts. Some show flashes of ideas that grew into their own fields, and others show that some things never change.

From the journals: JBC

Linking modified cysteines to cell migration. Recognizing protein tags for degradation. Disrupting C. difficile toxin production. Read about recent JBC papers on these topics.

Examining mechanisms of protein complex at a basic cell biological level

Mary Munson is co-corresponding author on a study revealing functions and mechanisms of the exocyst that are essential to how molecules move across a membrane through vesicles in a cell.