Proteins and proteomics

Of yeasts and men: One-hour proteomes, 10 years apart

To profile the human genome within an hour, the researchers used a new mass spectrometer and packed their liquid chromatography columns with very high pressure.

Does a protein hold the key to Alzheimer’s?

Researchers in Maryland and Massachusetts team up to study how SORL1 promotes tau trafficking and seeding in cells that leads to the neurodegenerative disorder.

MSU researchers leverage cryo-EM for decades-in-the-making breakthrough

Lee Kroos and Ben Orlando have reported the first high-resolution experimentally determined structures of the intramembrane protease SpolVFB.

What seems dead may not be dead

Vincent Tagliabracci will receive the Earl and Thressa Stadtman Distinguished Scientist Award at the ASBMB Annual Meeting, April 12–15 in Chicago.

Modified pea proteins are shaping the future of meat alternatives

University of Minnesota scientists use enzymes to mimic beef texture in plant-based protein.

Nobel for ‘breakthrough in biochemistry’

David Baker, Demis Hassabis and John M. Jumper received the chemistry prize for computational protein design and structure prediction.

From the Journals: JBC

Maternal metabolite promotes offspring survival. Unraveling the tick’s blood-sucking strategy. Connecting obesity and liver diseases. Read about these recent papers.

Mapping out the protein path to hearing

To determine the profile of inner hair cell proteins, a team of researchers develops a technique that optimizes proteomics for limited sample sizes.

From the journals: MCP

Among cells, communication is key. Silence of the peptide ions, Mapping the estrogen receptor interactome. Read about recent papers on these topics.