Annual Meeting

Disease discoveries in three realms
of the RNA world

RNA and disease: 2020 annual meeting track
Anita Hopper Takahiro Ito
By Anita Hopper and Takahiro Ito
Sept. 1, 2019

The RNA world is key to understanding gene expression in eukaryotes. This track will include three sessions describing exciting discoveries in RNA and disease: small noncoding RNAs, RNA modifications and RNA binding proteins.

The session on small noncoding RNAs will focus on discoveries in model systems and humans regarding transfer RNAs, tRNA fragments and Piwi-interacting RNAs regarding their biogenesis, functions, and roles in development and disease.

After transcription, nearly every type of RNA becomes decorated with nucleoside modifications; the RNA modification session will describe novel roles these modifications play in decoding, RNA stability and RNA regulation and activities. It also will describe how these modifications function in normal and aberrant biological states.

RNA functions rely on interactions with RNA binding proteins; the session on RNA binding proteins will describe how RNA-protein interactions regulate chromatin structure, transcription and splicing and how the interactions are involved in development and disease.

Keywords: small noncoding RNAs, RNA modification, RNA binding proteins, tRNA, piRNA, miRNA, tRNA fragments, gene expression, stem cells, muscle cells, development, cancer.

Who should attend: everyone who wants to learn how the RNA world impinges on gene expression in health and disease.

Theme song: “Hello, Goodbye” by the Beatles, because the song reminds us of the life of RNAs in a cell.

This track is powered by different kinds of RNAs — obviously.

Talks

  • tRNA: Splicing and subcellular dynamics — Anita Hopper, Ohio State University
  • The role of 3’tsRNAs in gene regulation — Mark Kay, Stanford University
  • The Piwi-piRNA pathway: A new paradigm in gene regulation — Haifan Lin, Yale University
  • piRNA biogenesis and function in Drosophila — Mikiko Siomi, University of Tokyo
  • RNA modification in cancer — Jianjun Chen, Beckman Research Institute of City of Hope
  • RNA modifications in health and disease — Tsutomu Suzuki, University of Tokyo
  • Acetylation of cytidine in messenger RNA regulates translation — Shalini Oberdoerffer, National Cancer Institute
  • tRNA quality control: Mechanisms, evolution, and implications for human disease — Eric Phizicky,University of Rochester Medical Center
  • RNA binding proteins in stem cells and cancer — Takahiro Ito, University of Georgia
  • The RNA exosome and genetic disease — Anita Corbett, Emory University
  • RNA, chromatin, and the coordinated control of gene expression — Tracy Johnson, University of California, Los Angeles
  • How mRNP composition determines mRNA fate — Guramrit Singh, Ohio State University

Enjoy reading ASBMB Today?

Become a member to receive the print edition four times a year and the digital edition weekly.

Learn more
Anita Hopper
Anita Hopper

Anita Hopper is a professor of molecular genetics at Ohio State University.

Takahiro Ito
Takahiro Ito

Takahiro Ito is an associate professor in the department of biochemistry and molecular biology at the University of Georgia.

Featured jobs

from the ASBMB career center

Get the latest from ASBMB Today

Enter your email address, and we’ll send you a weekly email with recent articles, interviews and more.

Latest in Careers

Careers highlights or most popular articles

Being a whole person outside of work
Hobbies

Being a whole person outside of work

Nov. 1, 2024

Creating art, community service, physical exercise, theater and music — four scientists talk about the activities that bring them joy.

Upcoming opportunities
Announcement

Upcoming opportunities

Oct. 31, 2024

Just added: Nominations are being accepted for FASEB's Excellence in Science Awards! Plus: Remember to register for the ASBMB Deuel conference, a must-attend event for lipids investigators.

Balancing research and classes in graduate school
Advice

Balancing research and classes in graduate school

Oct. 25, 2024

Our careers columnist talks to a doctoral candidate about managing lab and study time by carefully scheduling classes, getting to the lab early and “timeboxing.”

Upcoming opportunities
Announcement

Upcoming opportunities

Oct. 24, 2024

Friendly reminder: Early-decision abstracts for the 2025 ASBMB Annual Meeting are due by Oct. 30!

Industry partnership opportunities
Jobs

Industry partnership opportunities

Oct. 22, 2024

The deadlines for these are in November.

The molecular biology of commercial cannabis testing
Jobs

The molecular biology of commercial cannabis testing

Oct. 18, 2024

Anthony Torres of Front Range Biosciences, explains how scientists analyze organisms growing on the plant as well as the genetic markers in cannabis DNA.