Annual Meeting

Different field, different problem, same solution: metabolism!

A Discover BMB symposium: Advances in Organismal and Cellular Metabolism
Gary Patti Nika Danial
By Gary Patti and Nika Danial
Sept. 20, 2022

Metabolism has captured the interest of researchers across many different biological disciplines. In some fields, interest in longstanding metabolic questions has been renewed. In other areas, new metabolic connections are being made for the first time. No matter the topic, however, metabolism studies evoke pathway charts and methodological approaches that may not be common knowledge in all disciplines, and this could hinder dialogue between investigators. Moreover, many of the same metabolic patterns are observed consistently in different disease settings, animal models and cell types. 

The purpose of our symposium at Discover BMB, the annual meeting of the American Society for Biochemistry and Molecular Biology, which will be held in March in Seattle, is to bring together researchers from disparate areas of biology who speak the common language of metabolism. We want to facilitate interactions between investigators who may be thinking about the same metabolic themes, but who are not typically at the same meetings or conferences. The presentations will not be organized by discipline but rather by metabolism topic, with the aim of stimulating new discussions and collaborative opportunities.

Our symposium will feature research examining metabolism at multiple levels — ranging from whole body to cells and organelles. We will hear how the same metabolic programs are implicated not only in diseases such as cancer and neurodegeneration but also in fundamental biochemical processes including immune response and vision.

Keywords: Metabolism, metabolomics, lipids, physiology, interorgan communication, mitochondria, lysosomes, isotope tracing.

Who should attend: Anyone interested in metabolism at any level in any context.

Theme song: “What Makes You Beautiful” by One Direction, because metabolism lights up all of our worlds — and in honor of the infamous “What Makes Glycolysis” parody (look it up!).

This session is powered by ox phos (platinum-level sponsor) and substrate-level phosphorylation (gold-level sponsor).

Speakers

Metabolic physiology
Gary Patti (chair), Washington University in St. Louis
Deb Muoio, Duke University
Nada Kalaany, Harvard Medical School
Matt Gentry, University of Kentucky

Metabolism in health and disease
Jason Tennessen, Indiana University
Jing Fan, University of Wisconsin

Organelle metabolism
Nika Danial (chair), Harvard Medical School
Dale Abel, University of California, Los Angeles
Roberto Zoncu, University of California, Berkeley
Natalie Niemi, Washington University in St. Louis
 

 

Enjoy reading ASBMB Today?

Become a member to receive the print edition four times a year and the digital edition monthly.

Learn more
Gary Patti
Gary Patti

Gary Patti is a professor in the departments of chemistry and medicine at Washington University in St. Louis and the senior director of the Center for Metabolomics and Isotope Tracing.

Nika Danial
Nika Danial

Nika Danial is an associate professor of medicine at Dana–Farber Cancer Institute and Harvard Medical School and the co-director of the T32 training program in cancer chemical biology and metabolism at DFCI.

Get the latest from ASBMB Today

Enter your email address, and we’ll send you a weekly email with recent articles, interviews and more.

Latest in Science

Science highlights or most popular articles

Unraveling the language of histones
Profile

Unraveling the language of histones

Nov. 20, 2025

Philip Cole presented his research on how posttranslational modifications to histones are involved in gene expression and how these modifications could be therapeutically targeted to treat diseases like cancer.

How Alixorexton could transform narcolepsy treatment
News

How Alixorexton could transform narcolepsy treatment

Nov. 18, 2025

A new investigational drug, alixorexton, targets the brain’s orexin system to restore wakefulness in people with narcolepsy type 1. Alkermes chemist Brian Raymer shares how molecular modeling turned a lab idea into a promising phase 3 therapy.

Phosphatases and pupils: A dual legacy
Profile

Phosphatases and pupils: A dual legacy

Nov. 13, 2025

Yale professor Anton Bennett explores how protein tyrosine phosphatases shape disease, while building a legacy of mentorship that expands opportunity and fuels discovery in biochemistry and molecular biology.

Extracellular vesicles offer clues to cattle reproduction
Journal News

Extracellular vesicles offer clues to cattle reproduction

Nov. 11, 2025

Extracellular vesicles from pregnant cattle support embryo development better than laboratory models, highlighting their potential to improve reproductive efficiency in bovine embryo cultures. Read more about this recent MCP paper.

Proteomics reveals protein shifts in diabetic eye disease
Journal News

Proteomics reveals protein shifts in diabetic eye disease

Nov. 11, 2025

Using proteomics, researchers identified protein changes in eye fluid that mark diabetic retinopathy progression and may serve as biomarkers for vision-threatening complications. Read more about this recent MCP paper.

Protein modifications drive lung cancer resistance
Journal News

Protein modifications drive lung cancer resistance

Nov. 6, 2025

New assay enriches protein modifications in a single process, enabling detection of key changes in drug-resistant lung cancer cells that may guide future therapies.