The specialized metabolism and trafficking of cellular subcompartments

Your first biology course probably defined eukaryotes in part as having a group of specialized organelles. These membrane-bound subcompartments of the eukaryotic cell are unique in many ways, especially their specialized biochemistry and metabolism.

The three sessions we have organized for Discover BMB will cover several topics focused on the novel biology and biochemistry of the mitochondria, peroxisome and chloroplast. These sessions will address current research on specific metabolic pathways, with important new insights into the protein structure and trafficking that support the integrity and function of these organelles.

These multidisciplinary talks will provide information not only on the specific biochemical functions of these organelles, but also on their integrative architecture and physiology. In the three sessions, new information will be integrated into general principles of organelle biogenesis and metabolic function.

Keywords: Mitochondria, chloroplast, peroxisome, metabolism, covalent modifications, organelle biogenesis, protein structure and trafficking.

Who should attend: Anyone interested in metabolism, organellar proteomes and the specialized biology of organelles.

Theme song:  “The Cell” by Gojira, because it is such a high-energy song — mitochondria, chloroplasts ...

This session is powered by ATP. 

Mitochondria, peroxisomes and chloroplast metabolism

Protein covalent modifications and chloroplast metabolism

Chair: Greg Moorhead

Greg Moorhead, University of Calgary

Glen Uhrig, University of Alberta

R. Paul Jarvis, University of Oxford

Paula Mulo, University of Turku

Peroxisome biogenesis/metabolism

Chair: Tom Rapoport

Francesca Di Cara, Dalhousie University

Brooke Gardner, University of California, Santa Barbara

Tom Rapoport, Harvard Medical School; Howard Hughes Medical Institute

Irfan Lodhi, Washington University in St. Louis

Mitochondria energetics/metabolism

Chair: Erin Goley

Pere Puigserver, Dana–Farber Cancer Institute; Harvard Medical School

Lena Pernas, Max Planck Institute for Biology of Ageing

Alexey Amunts, Stockholm University

Rebecca Voorhees, California Institute of Technology