Which eight escaped the Scientific 16?
The Journal of Biological Chemistry’s Methods Madness tournament started off with a bang as last year’s finalist, #TeamMassSpec, faced off against the tournament newcomer #TeamFRET. #TeamFRET fought valiantly, but their supporters’ energy just didn’t transfer into votes. Meanwhile, #TeamMassSpec supporters turned up in SPECTRAcular numbers, pushing their team to the next round.
![](/getmedia/27d2ccdb-095f-43dd-81ca-ac166f1fcca7/MassSpecvFRET.png)
X-ray crystallographers around the world are rejoicing after #TeamXRC’s victory over #TeamImmuno. Votes proved to be too nonspecific for #TeamImmuno, whose supporters were unable to band together to provide support for their team. #TeamXRC advances to the next round while #TeamImmuno fades into the background.
![](/getmedia/760a7038-ecc3-464e-a7f9-3c2b57b23a79/ImmunovXRC.png)
#TeamCryo iced their competition, leaving #TeamMachine frozen in their tracks. Despite strategic support from #TeamMassSpec, it seems too many #TeamMachine supporters had their heads in the cloud, because they couldn’t find the algorithm needed to execute a win against the defending champion. #TeamCryo will move on to the Energetic Eight, where they will have a tough matchup against #TeamCRISPR.
![](/getmedia/4ff04f49-478c-4a88-8d36-335ffccde27a/CryovMachine.png)
In this cellular showdown, #TeamiPSC lacked the factors necessary to differentiate from the other losers of the week. In contrast, #TeamLiveCell was unphased by the pressure, shining bright in the win they captured. #TeamLiveCell has #TeamOmics in their frame as they focus on the next round.
![](/getmedia/d42a5095-5a2e-48dd-9087-5de7a2b629ca/LiveCellvIPSC.png)
#TeamPCR copied last year’s success to defeat #TeamChroma and advance to the next round. Supporters of #TeamChroma couldn’t match the flow rate of #TeamPCR voters, leaving #TeamChroma stuck in a stationary phase while their opponent mobilized. #TeamPCR will look to amplify their success with a win over #TeamMassSpec in the next round.
![](/getmedia/87771823-e7ee-4dfb-a795-176550904bea/PCRvChroma.png)
Resonating with their supporters, #TeamNMR put forth a dynamic performance to secure their second #JBCMethodsMadness win in as many years. Living up to their name, #TeamCloning replicated last year’s performance where they also lost against #TeamNMR in the first round. Perhaps they’ll find the winning recombination next year!
![](/getmedia/fd5ae858-98b5-4332-9601-dc4e1a8caf33/CloningvNMR.png)
#TeamCRISPR excised #TeamSuperRes in the first round of the tournament and will move on to the next round. Despite their resolution to make it further this year, the win that #TeamSuperRes pictured was never fully deconvolved. #TeamCRISPR has their work cut out for them, facing off against the defending champion #TeamCryo.
![](/getmedia/b94fca40-6962-464d-af20-1f7bc8dc910e/CRISPRvSuperRes.png)
Seq-ing a win in their tournament debut, #TeamOmics analyzed their competition and came out victorious. Seemingly unable to shed light on a winning formula, #TeamOpto failed to excite their supporters, resulting in their second tournament loss in as many years. Next, #TeamOmics will match up against #TeamLiveCell in the Energetic Eight round.
![](/getmedia/d19c1275-818c-42eb-b0c5-83726da7d222/OptovOmics.png)
Round 2: The Energetic Eight
Monday, March 22
12 p.m. Eastern – #TeamNMR vs. #TeamXRC
Tuesday, March 23
12 p.m. Eastern – #TeamPCR vs. #TeamMassSpec
Wednesday, March 24
12 p.m. – #TeamLiveCell vs. #TeamOmics
Thursday, March 25
12 p.m. – #TeamCryo vs. #TeamCRISPR
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