Contest

Third annual JBC Methods Madness tournament

Make your predictions by March 6 for a chance to win a $100 gift card
Stephanie Paxson
Feb. 25, 2022

Calling all scientists! The Journal of Biological Chemistry’s third annual Methods Madness tournament is finally here.

Last year’s tournament stirred up quite the rivalry, with #TeamMassSpec dethroning #TeamCryo as the #JBCMethodsMadness champion! This year we welcome new contenders, including #TeamFlow, #TeamMedicine and #TeamProtein. Will one of these newbies make it to the finals? You decide!

The madness begins on Monday, March 7. (See tournament schedule below.) Submit your bracket by Sunday, March 6, for a chance to win a $100 gift card. 

Round 1: The Scientific 16

Vote for your favorite methods by participating in polls posted by @jbiolchem.

Monday, March 7

9 a.m. – #TeamMassSpec vs. #TeamNMR

2 p.m. – #TeamXRC vs. #TeamImmuno

Tuesday, March 8

9 a.m. – #TeamChroma vs. #TeamFRET

2 p.m. – #TeamFlow vs. #TeamPCR

Wednesday, March 9

9 a.m. – #TeamCRISPR vs. #TeamOmics

2 p.m. – #TeamSuperRes vs. #TeamOpto

Thursday, March 10

9 a.m. – #TeamCryo vs. #TeamMedicine

2 p.m. – #TeamLiveCell vs. #TeamProtein

All times Eastern.

Enjoy reading ASBMB Today?

Become a member to receive the print edition four times a year and the digital edition monthly.

Learn more
Stephanie Paxson

Stephanie Paxson is the ASBMB’s journal marketing associate.

Get the latest from ASBMB Today

Enter your email address, and we’ll send you a weekly email with recent articles, interviews and more.

Latest in Science

Science highlights or most popular articles

Cholesterol as a novel biomarker for Fragile X syndrome
Journal News

Cholesterol as a novel biomarker for Fragile X syndrome

Nov. 28, 2025

Researchers in Quebec identified lower levels of a brain cholesterol metabolite, 24-hydroxycholesterol, in patients with fragile X syndrome, a finding that could provide a simple blood-based biomarker for understanding and managing the condition.

How lipid metabolism shapes sperm development
Journal News

How lipid metabolism shapes sperm development

Nov. 26, 2025

Researchers at Hokkaido University identify the enzyme behind a key lipid in sperm development. The findings reveal how seminolipids shape sperm formation and may inform future diagnostics and treatments for male infertility.

Mass spec method captures proteins in native membranes
Journal News

Mass spec method captures proteins in native membranes

Nov. 25, 2025

Yale scientists developed a mass spec protocol that keeps proteins in their native environment, detects intact protein complexes and tracks drug binding, offering a clearer view of membrane biology.

Laser-assisted cryoEM method preserves protein structure
Journal News

Laser-assisted cryoEM method preserves protein structure

Nov. 25, 2025

University of Wisconsin–Madison researchers devised a method that prevents protein compaction during cryoEM prep, restoring natural structure for mass spec studies. The approach could expand high-resolution imaging to more complex protein systems.

Method sharpens proteome-wide view of structural changes
Journal News

Method sharpens proteome-wide view of structural changes

Nov. 25, 2025

Researchers developed a method that improves limited proteolysis coupled with mass spectrometry, separating true changes from abundance or splicing effects.

Discoveries made possible by DNA
Feature

Discoveries made possible by DNA

Nov. 24, 2025

The discovery of DNA’s double helix revealed how genetic information is stored, copied and expressed. Revisit that breakthrough and traces how it laid the foundation for modern molecular biology, genomics and biotechnology.