In Memoriam

In memoriam: Edith C. Wolff

Stephanie Ramadan
By Stephanie Ramadan
May 20, 2024

Edith Clarke Wolff, an enzyme biochemist at the National Institutes of Health and a former assistant to the editor of the Journal of Biological Chemistry, died March 24. She was 94 and had been a member of the American Society for Biochemistry and Molecular Biology since 1986. 

Edith Wolff
Edith Wolff, when she worked for the Journal of Biological Chemistry as assistant to the editor.

Born November 1, 1929, in Brooklyn, New York, Edith Clarke attended Smith College before earning her Ph.D. in 1956 from Harvard Medical School/Radcliffe Graduate School, where she studied the effect of thyroxine on succinate oxidation. While at Harvard, she met her future husband, Jan Wolff, also a scientist. They married in 1955.

Edith Wolff conducted postdoctoral research at the NIH and then at the Medical Research Council’s National Institutes for Medical Research in the U.K. before taking a research position with the NIH in 1959. After working at the National Institute of Dental Research from 1959 to 1962, she stayed at home with her children until Herbert Tabor, then an associate editor for the JBC, asked her to oversee the journal’s flow of manuscripts.

“In those far-off days, everything was literally on paper,” Wolffe wrote in a remembrance for Tabor’s 100th birthday in 2018. “Manuscripts came in and went out by mail (quite expensive) or courier. Card files recorded which manuscripts went to which associate editors, tallied the number of manuscripts read by each member of the editorial board and marked the decisions. The index for each issue of the journal was punched into IBM cards. 

After Tabor was appointed the JBC’s editor-in chief in 1971, Wolff continued to oversee the journal’s editorial office until 1986. She then decided to return to research at the NIH, where she studied the unusual polyamine-derived amino acid hypusine. “Herb must have infected me with his fascination with polyamines,” she wrote. 

She retired from the NIH in 1998 but continued to work as a volunteer. 

Wolff was an avid walker, skier, hiker, swimmer, sailor and outdoor enthusiast, according to an obituary

She is survived by her husband of 68 years, Jan Wolff, a researcher at the National Institute of Diabetes and Digestive and Kidney Diseases. Also surviving are her children, Bretton R. Wolff and Renée S. Wolff and husband Aleksandar Milosavljevic-Cook; and grandchildren, Ellyn, Stefan, Lucas, Sofia, and Vivienne.

Enjoy reading ASBMB Today?

Become a member to receive the print edition four times a year and the digital edition weekly.

Learn more
Stephanie Ramadan
Stephanie Ramadan

Stephanie Ramadan is an assistant professor in human biology at the University of Wisconsin–Green Bay. Her research focuses on protein–protein interactions and novel method development. She is an ASBMB Today volunteer contributor.

Related articles

In memoriam: William L. Smith
Marissa Locke Rottinghaus
The ASBMB and me
Ralph A. Bradshaw

Get the latest from ASBMB Today

Enter your email address, and we’ll send you a weekly email with recent articles, interviews and more.

Latest in People

People highlights or most popular articles

Brain-on-a-chip tech powers neuroscience research
Profile

Brain-on-a-chip tech powers neuroscience research

Nov. 4, 2024

MOSAIC scholar Brian O'Grady has engineered a biomimetic model of the brain’s blood vessels to help tackle glioblastoma.

Being a whole person outside of work
Hobbies

Being a whole person outside of work

Nov. 1, 2024

Creating art, community service, physical exercise, theater and music — four scientists talk about the activities that bring them joy.

‘We’re thankful for our reviewers’
Journal News

‘We’re thankful for our reviewers’

Oct. 31, 2024

Meet some of the scientists who review manuscripts for the Journal of Biological Chemistry, Journal of Lipid Research and Molecular & Cellular Proteomics.

In memoriam: Bruce Ames
In Memoriam

In memoriam: Bruce Ames

Oct. 28, 2024

He invented a cheap and easy way to assess mutagenicity that helped identify many environmental and industrial carcinogens; it became known as the Ames test.

Honors for DebBurman, Margaryan and Santiago–Frangos
Member News

Honors for DebBurman, Margaryan and Santiago–Frangos

Oct. 28, 2024

The Council on Undergraduate Research honors Shubhik DebBurman with a mentoring award. Anush Margaryan wins a Projects for Peace grant to teach refugees in Armenia. UPenn names Andrew Santiago–Frangos an endowed assistant professor.

In memoriam: William L. Smith
In Memoriam

In memoriam: William L. Smith

Oct. 21, 2024

He served as associate editor of both the Journal of Biological Chemistry and the Journal of Lipid Research and was an ASBMB member for more than 40 years.