Essay

An unpredictable journey

Alex Toker
By Alex Toker
May 11, 2023

People often ask me how I got into science and biochemistry. I do not come from a family of scientists. Instead, my earliest recollection of exposure to science is as a teenager wandering around the displays and halls of the Natural History Museum and the Science Museum in London. For reasons that are hard to recollect, I was fascinated by all things of the natural world, and I spent hour upon hour every weekend in these two great museums diligently devouring all the knowledge I could find.

It therefore felt quite natural to study biology and biochemistry for my undergraduate degree at King’s College London and then pursue a Ph.D. in biochemistry at the National Institute for Medical Research, also in London. As luck would have it, I landed a postdoc in Lewis Cantley’s lab in Boston, first at Tufts University and thereafter at Harvard Medical School. That’s where my interests in cell and molecular biology and biochemistry solidified and, equally importantly, where I first encountered the Journal of Biological Chemistry and the American Society for Biochemistry and Molecular Biology.

In the mid-1990s, the JBC was still a print publication. Each week, Dr. Cantley would receive the large, distinctively light green JBC hard copy. He’d circle and label with the initials of each postdoc and student a manuscript in the table of contents that was relevant for us. That was our signal to read that paper. He performed this weekly routine much in the same way we now look at eTOCs in our emails.

Academic publishing has undergone a radical (re)evolution and change in the ensuing 30 years, but one thing has not changed: Since its inception in 1905, JBC has set the standard for high-quality, enduring research. It’s a journal for scientists, run by scientists, and owned and supported by the ASBMB, a society that formed shortly after JBC was founded and that, after more than 100 years, continues to support and advocate for science.

As a postdoc in the 1990s, I never could have predicted my own journey with the ASBMB. I was extremely proud to publish my papers in JBC as a trainee and then in my own lab, and as I transitioned to independence, I jumped at the chance to review JBC papers on an ad hoc basis whenever asked. Perhaps this was one reason I was formally invited to join the JBC editorial board, on which I served two terms.

As an EBM, I would review 60, 70, sometimes 80 papers in one year (something we no longer allow at JBC). At an ASBMB annual meeting, the inimitable Bob Simoni, a JBC associate editor, told me that one of the associate editors had coined the term “tokered” to describe the quantity and speed of JBC reviewing. Perhaps this is why I was invited to join the JBC board as an associate editor, and again I jumped at this opportunity.

After serving one and a half terms as an AE, I was delighted to be chosen as editor-in-chief, starting in fall 2021.

People often ask me, Why do you do all this work? I am a firm believer in academic science and society publishing and giving back to the scientific community. I am also a believer in many of the principles that guide the ASBMB and JBC in terms of publishing, advocating for science, promoting a culture of inclusivity and diversity, and ensuring the integrity of the published content in the three ASBMB journals.

Being an EBM, AE and EiC is a tremendous amount of work. We all are working scientists, with many demands on our time and countless commitments. But this work is incredibly rewarding. As active scientists in each of our communities, we play a major role in shaping the direction of the journal and ensure we maintain the standards of rigor, reproducibility and enduring science that ASBMB journals are known for.

I also have been privileged to meet and work with some extraordinary scientists over the years, most notably Herbert Tabor, who was JBC EiC for more than 40 years, and Lila Gierasch, my JBC EiC predecessor. The spirit of community and fraternity at the ASBMB and JBC is something I pay a great deal of attention to when it comes to recruiting new EBMs and AEs. This spirit is equally evident in the many staff members who have worked at the ASBMB over the years.

When I received news that I had been selected as a fellow of the ASBMB last year, I was incredibly honored but also tremendously humbled. Seeing my name alongside so many extraordinary scientists, many of whom I consider my science heroes, is something that teenager wandering around the museums in London some 40 years ago would never in his wildest imagination have predicted.

Other Fellow articles

Paul Craig: People in the ASBMB have changed my life

Susanna Greer: Saying yes to a community of communicators

Nathan Vanderford: Investing in the next generation

Ralph A. Bradshaw: The ASBMB and me

Enjoy reading ASBMB Today?

Become a member to receive the print edition four times a year and the digital edition weekly.

Learn more
Alex Toker
Alex Toker

Alex Toker is a professor and chief of the division of signal transduction in the departments of medicine and pathology and the cancer center at Beth Israel Deaconess Medical Center at Harvard Medical School as well as editor-in-chief of the Journal of Biological Chemistry and a 2022 ASBMB fellow.

Related articles

The ASBMB and me
Ralph A. Bradshaw
A journey with scientists
Daniel M. Raben
Bonding over biochemistry
F. Peter Guengerich
In memoriam: William L. Smith
Marissa Locke Rottinghaus
Water, you say?
Sephra Rampersad

Get the latest from ASBMB Today

Enter your email address, and we’ll send you a weekly email with recent articles, interviews and more.

Latest in Opinions

Opinions highlights or most popular articles

Benefits of attending a large scientific conference
ASBMB Annual Meeting

Benefits of attending a large scientific conference

Feb. 13, 2025

Researchers have a lot of choices when it comes to conferences and symposia. A large conference like the ASBMB Annual Meeting offers myriad opportunities, such as poster sessions, top research talks, social events, workshops, vendor booths and more.

When Batman meets Poison Ivy
Science Communication

When Batman meets Poison Ivy

Feb. 13, 2025

Jessica Desamero had learned to love science communication by the time she was challenged to explain the role of DNA secondary structure in halting cancer cell growth to an 8th-grade level audience.

The monopoly defined: Who holds the power of science communication?
Essay

The monopoly defined: Who holds the power of science communication?

Feb. 12, 2025

“At the official competition, out of 12 presenters, only two were from R2 institutions, and the other 10 were from R1 institutions. And just two had distinguishable non-American accents.”

How I made the most of my time as an undergrad
Essay

How I made the most of my time as an undergrad

Jan. 30, 2025

An assistant professor of biology looks back at the many ways he prepared (or didn’t) for his future when he was in college.

I find beauty in telling stories about giants
Science Communication

I find beauty in telling stories about giants

Jan. 29, 2025

Andrea Lius wished she could find a focus for her scientific research — until she realized that what she really liked was talking to other scientists about the focus of their work.

Leveraging social media to share science
Science Communication

Leveraging social media to share science

Jan. 23, 2025

Scientist and educator Elisabeth Marnik explains how to combat misinformation, such as the popular myth that drinking bleach will prevent infections.