Essay

The power of sabbaticals

A story of career reinvention and reinvigoration
Nicholas Rhind
By Nicholas Rhind
March 28, 2024

One of the great opportunities in academic science is reinventing one's research program. In my case, sabbaticals have not led to dramatic shifts in fields. Instead, they have allowed me to visit three collaborators’ labs and learn new techniques that have empowered my lab to pursue new questions.

My first “sabbatical” actually happened before I started my independent career. I was hired by the University of Massachusetts Medical School in July 2001, but my lab in the new research building would not be ready until November. So, I accepted a generous invitation to spend three months at the Institut Pasteur learning how to comb DNA, an elegant single-molecule technique that changed the way I thought about the regulation of DNA replication.

Nicholas Rhind
Nicholas Rhind

Fast forward 11 years: I was a tenured associate professor and interested in the biochemical mechanism underlying the regulation of DNA replication that we have characterized by DNA combing. By this time I had a family, which made a foreign sabbatical impractical. I looked closer to home, and arranged to spend a year in Johannes Walter's lab at Harvard Medical School, learning how to do replication biochemistry in frog embryo extracts. It was like being a postdoc again, trying to figure out how to make a project work in an environment with all of the support and expertise I needed.

After my first two visiting-scientist experiences, I was keen for a third. Constrained still to Eastern Massachusetts, nine years after my stint at HMS, I arranged to spend a year in Jeff Gelles’ lab at Brandeis. Gelles has pioneered single-molecule fluorescence microscopy, and I wanted to use the approach to test models we had about the loading of proteins at replication origins. I had another fantastic experience. A student has since established the technology in our lab, allowing us to test models we have been speculating about for years.

My primary takeaway: Sabbaticals are a precious resource. 

All sorts of constraints can make them tricky to pull off — I delayed my third sabbatical a few years because of funding and staffing consideration — but the effort is well worth making. I was amazed at how much time I had to think and work when I was away from my office. I knew that not having teaching or committee responsibilities would free up lots of time. An unanticipated benefit was that not reviewing papers or grants for a year created more free time, and free mental energy, than I could have imagined. And none of the journal editors or granting agencies complained. They all said, “That's great. Have fun. Let me know when you are back in your office.” 

Being local, I was able to spend one day a week at UMass to have group meetings, talk with folks and look at data. My lab carried on fine, and I am sure they would have been just as fine if I had been somewhere else, meeting by Zoom.

If you’re fortunate enough to have access to a sabbatical, don't waste it. Use it to reinvent your lab in some small way, and enjoy yourself while you do so.

Career reinvention and reinvigoration: four stories

To mark Women’s History Month, four members of the American Society for Biochemistry and Molecular Biology’s Women in Biochemistry and Molecular Biology Committee, known as the WIBMB, have written personal essays about their career journeys.

Read them all:

Pursuing the call to change by Karlett Parra

Catalyzing change and redefining purpose by Sudha Sharma

Building community by Megan Filbin

The power of sabbaticals by Nicholas Rhind

Enjoy reading ASBMB Today?

Become a member to receive the print edition four times a year and the digital edition monthly.

Learn more
Nicholas Rhind
Nicholas Rhind

Nick Rhind is a professor of biochemistry and molecular biotechnolog, at the University of Massachusetts Chan Medical School. He is a member of the ASBMB WIBMB Committee.

Featured jobs

from the ASBMB career center

Get the latest from ASBMB Today

Enter your email address, and we’ll send you a weekly email with recent articles, interviews and more.

Latest in Careers

Careers highlights or most popular articles

Melissa Moore to speak at ASBMB 2025
ASBMB Annual Meeting

Melissa Moore to speak at ASBMB 2025

April 2, 2025

Richard Silverman and Melissa Moore are the featured speakers at the ASBMB annual meeting to be held April 12-15 in Chicago.

Engineering the future with synthetic biology
ASBMB Annual Meeting

Engineering the future with synthetic biology

March 31, 2025

Learn about the ASBMB 2025 symposium on synthetic biology, featuring applications to better human and environmental health.

Host vs. pathogen and the molecular arms race
ASBMB Annual Meeting

Host vs. pathogen and the molecular arms race

March 28, 2025

Learn about the ASBMB 2025 symposium on host–pathogen interactions, to be held Sunday, April 13 at 1:50 p.m.

Richard Silverman to speak at ASBMB 2025
ASBMB Annual Meeting

Richard Silverman to speak at ASBMB 2025

March 27, 2025

Richard Silverman and Melissa Moore are the featured speakers at the ASBMB annual meeting to be held April 12-15 in Chicago.

Women’s History Month: Educating and inspiring generations
Observance

Women’s History Month: Educating and inspiring generations

March 27, 2025

Through early classroom experiences, undergraduate education and advanced research training, women leaders are shaping a more inclusive and supportive scientific community.

Upcoming opportunities
Announcement

Upcoming opportunities

March 26, 2025

Register for the May 14 ASBMB Breakthroughs webinar on biosynthesis and regulation of plant phenolic compounds.