Structural biology of proteins and subcellular structures
For decades, determining macromolecular structures has been pivotal in deciphering the complexities of biology and cell signaling. The evolution of computational methods and imaging has transformed our study of challenging macromolecules and cellular architectures. This theme will spotlight how structural biologists use complementary approaches to unveil insights into the intricacies of diverse and dynamic cellular systems that govern life itself.
Organizers
Christopher Barnes
Stanford University
Breann Brown
Vanderbilt University
Symposia
Structural approaches to address human health
- The structural basis for receptor signaling as a blueprint for biologics
Daryl Klein, Yale University - Structural and biochemical approaches to study the nsp16-nsp10 methyltransferase from coronaviruses
Monica Rosas–Lemus, University of New Mexico - Structural characterization of bacterial lipoproteins
Naima Sharaf, Stanford University - TBD
Jonathan Abraham, Harvard University
Biomolecular complexes and allostery
- Investigating the allosteric control of heme biosynthesis
Breann Brown, Vanderbilt University - Harnessing protease conformational dynamics for detection and treatment of viral infection
Jeanne Hardy, University of Massachusetts Amherst - The intrinsic structural dynamics of a histone deacetylase enzyme dictate enzymatic activity and inhibition
D. Flemming Hansen, Francis Crick Institute - Structure and function of encapsulin nanocompartments
Tobias Giessen, University of Michigan Medical School
Advances in integrative structural biology
- Structure-guided approaches to engineer broad immunotherapies against emergent viruses
Christopher Barnes, Stanford University - Mapping mitochondrial protein import in cells
Danielle Grotjahn, Scripps Research Institute - Developing correlative cryo-EM technologies to support in situ structural biology
Elizabeth Wright, University of Wisconsin, Madison - Discovering and validating the biology of superdark transmembrane proteins using millions of AlphaFold2 structure predictions
Daniel Isom, University of Miami Miller School of Medicine
Other sessions
These sessions and activities will also be of interest. See the full program schedule for details on these and the rest of the ASBMB Annual Meeting.
Featured speakers
- Persistence and serendipity in science: a poker analogy
Melissa J. Moore, University of Massachusetts Chan Medical School - Novel GABA aminotransferase and ornithine aminotransferase inactivators as potential new treatments for epilepsy, pain and hepatocellular carcinoma
Richard Silverman, Northwestern University - Phase separation in cells: Insights from biophysical computations
Rohit V. Pappu, Washington University in St. Louis
Meetups
- Cell and developmental biology
- Computational biology, predictive technology and AI
- Drug discovery and pharmacology
- Industry scientists and industry interest
- Proteins
Interest group sessions
- Protein design, expression and production for drug discovery: Industry perspectives
- Protein function prediction and design using large language models
Workshops
- Advocacy town hall
- Four interpretable machine learning techniques to immediately accelerate your biological research
- Use of virtual reality for biomolecular visualization in 3D
Poster sessions
- Cell and developmental biology
- Computational biology, predictive technology and AI
- Drug discovery and pharmacology
- Proteins
Events
- ASBMB welcome address
- Career and education fair
- Emerging investigator seminar
- Undergraduate poster competition
Make more possible
There's a whole lot more to the meeting beyond your symposium theme.
Explore the program schedule
