Themes

Lipids and membranes

Lipids are fundamental building blocks of life. Their unique chemical properties drive many core cellular processes. Their self-organization in the aqueous environment enables membrane-bound cells to exist and facilitates organelle compartmentalization. They are an exquisitely high-yield energy source, which is both efficiently stored, highly stable and rapidly mobilized. Their vast array of unique chemical configurations enables them to function as both first and second messenger molecules.

Dysfunction of lipid abundance and signaling is a hallmark of metabolic diseases including Type 2 diabetes, cardiovascular disease, cancer and neurodegenerative disease. Understanding both the basic and disease-driving function of lipids is important to establish cellular regulation and disease etiology.

Organizers

Gerry Hammond

Gerry Hammond
University of Pittsburgh

Judith Simcox

Judith Simcox
University of Wisconsin

Symposia

Sunday, April 13

New frontiers in inositol lipid signaling

  • Lipid switches in cell physiology: From nutrient signals to disease
    Volker Haucke, Leibniz Forschungsinstitut für Molekulare Pharmakologie
  • The sub cellular landscape of PI3K activation at single molecule resolution
    Gerry Hammond, University of Pittsburgh
  • PI3K signaling in health and disease: New twists and turns 
    Ralitsa Madsen, University of Dundee
  • Phosphoinositide signaling as a dynamical system
    Min Wu, Yale University
Monday, April 14

Emerging roles for lysosomal lipids in metabolic disease

  • Mechanisms and physiology of lysosomal lipid degradation
    Robert Farese, Memorial Sloan Kettering Cancer Center
  • Lysosome cholesterol sensing in growth regulation
    Hijai Shin, University of Texas Southwestern Medical Center
  • Novel regulators of lysosomal lipids and their role in neurodegeneration
    Monther Abu-Remaileh, Stanford University
  • Lipid trafficking in Parkinson’s Disease
    Suzanne Pfeffer, Stanford University School of Medicine
Tuesday, April 15

Novel insights into neurodegeneration from lipid biology

  • Lipid mediators of Alzheimer's disease: A tale of mice and men
    Judith Simcox, University of Wisconsin–Madison
  • Lipid signaling in neurodegeneration
    Eamonn Dickson, University of California, Davis
  • Mitochondrial quality control in neuronal homeostasis and neurodegenerative disease
    Chantell Evans, Duke University
  • The lipidome landscape in models of Niemann-Pick Type C
    Stephanie Cologna, University of Illinois at Chicago

Other sessions

These sessions and activities will also be of interest. See the full program schedule for details on these and the rest of the ASBMB Annual Meeting.

Featured speakers

Meetups

  • Glycobiology and extracellular matrices
  • Industry scientists and industry interest
  • Lipids and membranes
  • Neurobiology

Interest group sessions

Workshops

Poster sessions

  • Glycobiology and extracellular matrices
  • Lipids and membranes
  • Neurobiology

Events

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