Chemical tools to reveal new biology
Chemical biology is a powerful interdisciplinary bridge linking basic and translational research. This includes the development of new chemical modalities, which open the door to performing research at a biochemical resolution in the appropriate physiological context, leading to the discovery of fundamental biological processes as well as new therapeutic modalities. This track focuses on cutting-edge chemical technologies developed and applied toward understanding, modulating and controlling biological systems.
Organizers
George Burslem
University of Pennsylvania
Yael David
Memorial Sloan Kettering Cancer Center
Symposia
Epigenetic chemical biology
- TBD
Sai Gourisankar, Stanford University - Uncovering cancer-associated epigenetic events using novel chemical tools
Yael David, Memorial Sloan Kettering Cancer Center - Mechanism-based approaches for targeting histone reader proteins
Marcey Waters, University of North Carolina at Chapel Hill - TBD
Tatiana Kutateladze, University of Colorado
Chemical biology for therapeutics
- Accelerating DUB inhibitor discovery
Sara Buhrlage, Harvard University - Targeting histone “reader” subunits of chromatin remodeling complexes in disease
Emily C. Dykhuizen, Purdue University - New approaches to target undruggable proteins
Jian Jin, Icahn School of Medicine at Mount Sinai - Unveiling potent inhibitors for protein N-terminal methyltransferase
Rong Huang, Purdue University
New accessible chemical technologies
- Chemical-proteomic strategies to investigate reactive cysteines
Eranthie Weerapana, Boston College - Post-translational editing of proteins in mammalian cells
George Burslem, University of Pennsylvania - Genetic code expansion technology for all that want to reveal new biology
Ryan Mehl, Oregon State University - Chemical tools for biological discoveries
Monika Raj, Emory University
Other sessions
These sessions and activities will also be of interest. See the full program schedule for details on these and the rest of the ASBMB Annual Meeting.
Featured speakers
- Persistence and serendipity in science: a poker analogy
Melissa J. Moore, University of Massachusetts Chan Medical School - Novel GABA aminotransferase and ornithine aminotransferase inactivators as potential new treatments for epilepsy, pain and hepatocellular carcinoma
Richard Silverman, Northwestern University - Expanding the kinome
Vincent Tagliabracci, University of Texas Southwestern Medical Center
Meetups
- Chemical biology
- Industry scientists and industry interest
- Neurobiology
- Proteomics and mass spec
Interest group sessions
- Biochemistry and climate change: Molecular responses and innovations
- Citrullination and acetylation: Unveiling PTMs cross-talk in neurodisease
- Protein design, expression and production for drug discovery: Industry perspectives
- The dynamic actin cytoskeleton in cancer metastasis
Workshops
Poster sessions
- Chemical biology
- Neurobiology
- Omics
Events
- ASBMB welcome address
- Career and education fair
- Emerging investigator seminar
- Undergraduate poster competition