Sept. 29 – Oct. 2, 2022 | Snowbird, Utah
Transcriptional Regulation
Chromatin and RNA Polymerase II
Transcriptional regulation: Chromatin and RNA polymerase II
Sept. 29 – Oct. 2, 2022 | Snowbird, Utah
Sessions will cover recent advances and new technologies in RNA polymerase II regulation, including the contributions of non-coding RNAs, enhancers and promoters, chromatin structure and post-translational modifications, molecular condensates, and other factors that regulate gene expression. Dr. Patrick Cramer of the Max Planck Institute will present the keynote address on the structure and function of transcription regulatory complexes.
The meeting is highly interactive and collaborative. Attendees will include principal investigators, postdoctoral fellows, students, and scientists from the pharmaceutical and biotech industries. Students and postdoctoral fellows are especially encouraged to attend and will be eligible for poster awards. Poster award winners will be given an opportunity to present their work as a short talk toward the end of the meeting.
Conference information
- Conference will begin around 5 p.m. on Sept. 29.
- Conference will conclude around 11 p.m. on Oct. 2.
- If you choose a room with us during the registration process your check-in date will be Thursday, Sept. 29 and your check-out date will be Monday, Oct. 3.
- There are only a few rooms available at the venue and rooms will be assigned on a first come first served basis.
Important dates
| Aug. 28 | Registration deadline |
|---|
Organizers
JBC virtual issue
RNA polymerase II and transcriptional regulation
A selection of articles published in the Journal of Biological Chemistry in recent years to showcase advances and new technologies in RNA polymerase II regulation.
Sponsors
Sponsorship opportunities
Become a sponsor of the ASBMB Transcriptional Regulation: Chromatin and RNA Polymerase II symposium. It’s the most effective way to reach key decision makers in the fields of transcription, chromatin biology, imaging, genomics and epigenetics.
What’s included
The full conference package includes:
- All scientific sessions, poster sessions and meeting materials.
- 4 nights lodging at Snowbird Ski & Summer Resort (arriving Sept. 29, departing Oct. 3).
- 1 complimentary tram ticket per attendee to use at their leisure during the meeting dates.
Note: Lodging is not included in commuter registration rates.
Registration changes
Registration changes will be accepted as space allows until Aug. 29, 2022, and can be made by contacting meetings@asbmb.org.
Cancellation policy
Cancellations received in writing on or before Aug. 29, 2022, are subject to a $100 processing fee. No refunds will be issued for cancellations after Aug. 29, due to final guarantee commitments. Email meetings@asbmb.org and attach a copy of your meeting registration receipt/paid invoice.
Important health and safety information
- As of Sept. 29, 2022, mask wearing is not required at the conference following local and state guidelines. We encourage attendees to wear a mask and should this policy change we will update attendees immediately via email.
- Each attendee will receive one KN95 mask in their conference bag at badge pickup.
- All attendees are required to show a proof of vaccination when checking in at the conference badge pickup desk onsite at the meeting. Badges must be worn during the duration of the conference.
- Registered attendees who do not show their proof of vaccination and don’t wear their badge will not be permitted to attend the meeting.
- Accepted COVID-19 vaccines as defined by the CDC and WHO.
- Vaccination proof accepted in forms of digital QR code, photo on phone, and physical copy of vaccination card.
- Prior to checking in, at least 24 hours in advance of badge pickup, we encourage attendees to perform their own rapid antigen tests. You should alert ASBMB staff if you test positive and/or experience COVID-19 symptoms before checking in onsite at the badge pickup desk and refrain from attending the meeting.
- Should you feel sick, show symptoms or test positive during the conference please alert ASBMB staff and refrain from attending the conference.
Speaker instructions
- Session room will be equipped with standard projection equipment which includes data projector, desktop computer and several adaptors — including HDMI cable, clicker, laser pointer — and a technician.
- Check in with the AV tech in the room at least 30 minutes prior to the session your talk is in.
- Bring your presentation on a readable USB flash drive. The AV tech will assist you in loading it onto the provided desktop computer.
- Bring your laptop and HDMI cord or adapters if you want to give your talk with your own computer.
- When preparing your presentation, please use standard fonts (e.g., Times New Roman, Arial, Helvetica, etc.). If you are using a font that is not standard it should be embedded into your PowerPoint presentation.
- Create your presentation using 16:9 aspect ratio.
- In the same folder as your presentation, include any external files that are used in the presentation, e.g. video files. Copy the entire folder to a USB flash drive.
- Test your presentation on a separate laptop to ensure that the fonts are standard and that components such as movies are included rather than linked in your presentation.
- Microphones in the session room are provided to ensure that everyone can clearly hear the presentations. Presenters should be mindful of those who are hard of hearing and always use the supplied microphones.
- If you choose to present with your own laptop you must provide your own adapter to HDMI connections.
Poster presenters
- Poster boards are 4’x8’ and the useable space is 45”x91”.
- Push pins will be provided.
- Poster presentations are scheduled on two days of the conference, Friday, Sept. 30, and Saturday, Oct. 1, from 8–10 p.m.
- Set up your poster between 7–8 a.m. the morning of your scheduled poster presentation date.
- Take down your poster at the conclusion of your poster presentation time slot.
- Posters that are left up after your poster presentation session will be discarded.
- Poster presentation dates and times cannot be switched.
Meeting location
Snowbird Ski & Summer Resort
Highway 210, Little Cottonwood Canyon
Snowbird, UT, 84092
USA
1-800-232-9542
All meeting sessions and events are scheduled in the Cliff Lodge, Entry #4.
Snowbird Resort is now cashless. All points of sale at Snowbird restaurants, retail stores, lodging properties, the spa, summer activities, parking and valet are cashless. Snowbird is accepting credit, debit and mobile pay only. Reverse ATMs are available at no charge and are located at the Snowbird Center on Level 1 next to Wings and on Level 2 in the Snowbird Center lounge along with The Cliff Lodge lobby. Prepaid debit cards from the Reverse ATMs are accepted anywhere, not just Snowbird.
What is Snowbird's elevation?
Snowbird’s base elevation, at the Snowbird Center, is 8,100 feet. Snowbird’s highest point is at Hidden Peak, where the tram docks — a whopping 11,000 feet.
Some tips for acclimating to the higher elevation: stay hydrated, consume foods rich in potassium, limit salt intake and give yourself a break from strenuous exercise until you've had a chance to adjust.
Oktoberfest at Snowbird
On our free afternoon, enjoy Oktoberfest activities. See the event description and map.Getting to Snowbird
Closest airport
Salt Lake City International Airport (SLC) is approximately 40 minutes from Snowbird.
Airport shuttle service
It is the responsibility of each attendee to arrange for their transportation to the Snowbird resort from the airport and back to the airport from the Snowbird resort.
Canyon Transportation — provide your Snowbird housing confirmation when booking the shuttle.
800-453-3000 US toll free
00-800-4400-5511 International
Directions
From Salt Lake City International Airport
Take I-80 east to I-215 south. Take Exit 6 (6200 South) and go east on 6200 South, toward the mountains. This road will lead you straight to UT-210 and up Little Cottonwood Canyon to Snowbird.
From downtown Salt Lake City
Go west on 500 South to I-15 and head south. Exit at I-215 heading east. Get off at Exit 6 (6200 South) and go east on 6200 South, toward the mountains. This road will lead you straight to UT-210 and up Little Cottonwood Canyon to Snowbird.
From points South
Take I-15 north to Exit 295 (9000 South). Turn right onto 9000 South. This street becomes 9400 South, which takes you to the mouth of Little Cottonwood Canyon. Go right on UT-210. Six miles to Snowbird.
From Park City
Take UT-224 west and north to I-80. On I-80, head west toward the Salt Lake Valley. Take Exit 130 to I-215 south. Get off at Exit 6 (6200 South) and go east on 6200 South, toward the mountains. This road will lead you straight to UT-210 and up Little Cottonwood Canyon to Snowbird.
Program schedule
Thursday September 29
Friday September 30
Saturday October 1
Sunday October 2
Thursday September 26
Friday September 27
Saturday September 28
Sunday September 29
Thursday agenda
Badge pickup
Badge pickup and session rooms are located on the lower level L1 of the cliff lodge.
Dinner
Attendees are required to pick up their badge prior to attending dinner. You cannot attend dinner without your badge. Primrose is located on the lobbly level L right by the resort checkin.
Welcome and opening remarks by organizers
Session I: Structure/function of transcription complexes
Session chair: Catherine Musselman
Structural basis of nucleosome retention during transcription
Lucas Farnung, Harvard Medical School
Single molecule analysis of RNApII transcription reveals unexpected features of transcription activation and PIC assembly
Stephen Buratowski, Harvard Medical School
Regulating transcription by chromatin-bound PP2A
Alessandro Gardini, Wistar Institute
Mechanism of the INO80 ATP-dependent chromatin remodeling complex
Geeta Narlikar, University of California, San Francisco
CK2-mediated phosphorylation of SUZ12 promotes PRC2 function by stabilizing enzyme active site
Xin Liu, University of Texas Southwestern Medical Center
Welcome networking reception
Attendees are required to pick up their badge prior to attending the reception. You cannot attend the reception without your badge.
Friday agenda
Badge pickup
Badge pickup and session rooms are located on the lower level L1 of the cliff lodge.
Breakfast
Session II: Transcription factors
Session chair: Peter Verrijzer
Mechanisms and impact of transcription factor interactions with nucleosomes
Ken Zaret, University of Pennsylvania
Genome-wide functions of yeast DNA sequence-specific transcription factors
Steven Hahn, Fred Hutchinson Cancer Center
Histone modifications regulate pioneer transcription factor binding and cooperativity
Mario Halic, St. Jude Children’s Research Hospital
The oncogenic transcription factor ERG utilizes distinct positive feedback loops to mediate diverse cell fates
Peter Hollenhorst, Indiana University
Mechanism underlying binding selectivity of pioneer factors
Lu Bai, Pennsylvania State University
Networking break
Session III: Transcription initiation
Session chair: Shannon Lauberth
Mechanistic studies of TFIIH kinase CDK7 reveal regulatory roles at multiple transcriptional stages
Dylan Taatjes, University of Colorado Boulder
Mechanisms of RNA Polymerase II transcription
Craig Kaplan, University of Pittsburgh
RNA Polymerase II pausing coordinates stage-selective cell cycle progression and erythroid differentiation
Stirling Churchman, Harvard Medical School
In vivo contribution of the DPE core promoter motif to transcriptional regulation in developing Drosophila melanogaster embryos
Tamar Juven–Gershon, Bar-Ilan University
Distinct architectures of induced, poised and constitutive yeast promoters reveal an integrated SAGA and TFIID PIC assembly pathway during induction
Frank Pugh, Cornell University
Lunch
Session IV: RNA Pol II and post-translational modifications
Session chair: Stirling Churchman
Chemical approaches to understanding reversible lysine modifications
Philip Cole, Harvard Medical School
New insights into the mono-ADP-ribosyltransferase function of SIRT6
Katharine Diehl, University of Utah
Spatiotemporal recruitment of transcription regulators by the post-translational modifications on RNA Polymerase II
Y. Jessie Zhang, University of Texas at Austin
Co-evolution of the Ess1-CTD axis in polar fungi suggests a role for phase separation in cold tolerance
Steven Hanes, SUNY Upstate Medical University
An acetylation-mediated chromatin switch governs H3K4 methylation read-write capability
Brian Strahl, University of North Carolina
Networking break
Session V: Transcription elongation
Session chair: Lucas Farnung
Probing the direct effects of the Paf1 complex on transcription and chromatin
Karen Arndt, University of Pittsburgh
RNA modifications in R-loops regulate the pausing of elongating RNA Polymerase II in non-coding RNA
Jason Watts, National Institute of Environmental Health Sciences
An optimal Pol II position for co-transcriptional splicing restricts gene output when splicing is less efficient
Karla Neugebauer, Yale University
Molecular basis of transcription blockage, transcription-couples damage recognition and repair
Dong Wang, University of California, San Diego
The roles of FACT during transcription elongation
Francois Robert, IRCM
Dinner
Poster session I & reception
Saturday agenda
Badge pickup
Badge pickup and session rooms are located on the lower level L1 of the cliff lodge.
Breakfast
Keynote lecture
Mechanisms of chromatin transcription
Patrick Cramer, Max Planck Institute for Multidisciplinary Sciences
Session VI: Enhancers
Session chair: Allesandro Gardini
Architecture, identification and functional features of active human enhancers
John Lis, Cornell University
SWI/SNF and its AT-hook is required for de novo enhancer activation in cell lineage priming
Blaine Bartholomew, M.D. Anderson Cancer Research Center
Hormone-induced enhancer assembly requires an optimal level of multivalent interactions
Zhijie "Jason" Liu, University of Texas Health Science Center at San Antonio
Nucleation and spreading rejuvenate polycomb domains every cell cycle
Srinivas Ramachandran, University of Colorado School of Medicine
Role of enhancer RNAs in the estrogen-regulated control of enhancer assembly and function in breast cancer cells
W. Lee Kraus, University of Texas Southwestern Medical Center
Networking break
Session VII: Structure/function of transcription complexes II
Session chair: Courtney Hodges
Nucleosome assembly disassembly, and stacking
Karolin Luger, University of Colorado Boulder
Swi-Snf represses sulfur metabolism gene transcription by promoting cysteine biosynthesis
Michael Church, Stowers Institute for Medical Research
Nucleosome conformation dictates the histone code
Catherine Musselman, University of Colorado Anschutz Medical Campus
Structure and function of a bacterial histone lysine methyltransferase in pathogenesis
Raymond Trievel, University of Michigan
What a double-headed histone methyl transferase enzyme can teach us about writing and reading gene repressive marks on chromatin
Bassem Al-Sady, University of California, San Francisco
Lunch on own with free time to explore Snowbird
Yoga
Space is on a first come, first served basis due to limited yoga mats available and is complimentary for registered conference attendees. Attendees are required to sign a liability form prior to attending. Conference badge required.
Dinner
Poster session II & reception
Sunday agenda
Breakfast
Session VIII: Chromatin, Pol II and non-coding RNA
Session chair: Laura Banaszynski
The pausing zone, the torpedo and control of RNA Polymerase II elongation and termination
David Bentley, University of Colorado School of Medicine
The lncRNA Firre functions as a transcriptional activator
John Rinn, University of Colorado Boulder
Exploration of the regulation of transcription by RNA Polymerase II
James Kadonaga, University of California, San Diego
Competition for H2A.Z between genes and repetitive elements establishes transcriptional response to anti-viral immune activation
Patrick Murphy, University of Rochester
Analysis of the human Ccr4-Not complex
Joseph Reese, Pennsylvania State University
Role of enhancer RNAs in the estrogen-regulated control of enhancer assembly and function in breast cancer cells
W. Lee Kraus, University of Texas Southwestern Medical Center
Networking break
Session IX: Imaging and emerging techniques
Session chair: Benjamin Sabari
Single-molecule dynamics of chromatin remodelers and transcription factors
Carl Wu, John Hopkins University
Multifactorial chromatin regulatory landscapes at single cell resolution in development
Michael Meers, Washington University School of Medicine St. Louis
Connecting transcriptional regulation to transcription factor dynamics: MYC, bursting and kinetic proofreading
Daniel Larson, National Cancer Institute
Development of a novel class of epigenetic sensors for cut&run
Bryan Venters, EpiCypher
Super-resolution imaging of transcription in live mammalian cells
Ibrahim Cissé, Max Planck Institute
Single-molecule and single-cell epigenetics: Decoding the epigenome for cancer research and diagnostics
Efrat Shema, Weizmann Institute of Science
Lunch
Session X: Chromatin organization and partitioning
Session chair: Katharine Diehl
The role of noncoding RNAs in cancer: shedding light on the transcriptomic dark matter
Shannon Lauberth, Northwestern University
Functional partitioning of transcriptional regulators by patterned charge blocks
Benjamin Sabari, University of Texas Southwestern Medical Center
Circadian transcription factors rhythmically regulate stereotypic chromatin conformations at enhancers
Jerome Menet, Texas A&M University
Investigating the methyl-CpG binding protein ZBTB4 in mediating epigenetic-based transcriptional processes
Bethany Buck–Koehntop, University of Utah
Dosage matters: Regulation, dynamics and consequences of histone H2A ubiquitylation
Peter Verrijzer, Erasmus University Rotterdam
Networking break
Session XI: Genome architecture
Session chair: Srinivas Ramachandran
Effects of histone H2B ubiquitylations and H3K79 tri-methylation on the kinetics of transcription through the nucleosome investigated with single-molecule FRET
Tae-Hee Lee, Pennsylvania State University
Global repression and variable compensation following inhibition of mammalian SWI/SNF
Benjamin Martin, Harvard Medical School
Loss of heterochromatin at endogenous retroviruses creates competition for transcription factor binding
Laura Banaszynski, University of Texas Southwestern Medical Center
Dynamic chromatin conformations underlie transcriptional coupling of distant regulatory genes in living embryos
Michal Levo, Princeton University
Dynamic reactivation of the G1 enhancer landscape underlies SWI/SNF addiction
H. Courtney Hodges, Baylor College of Medicine
Dinner
Poster prize winners announced
Poster prize oral presentations
Session XII: Disease and therapeutics
Session chair: Jason Watts
Integrated single-cell multiomic analysis of HIV latency reversal reveals novel regulators of viral reactivation
Edward Browne, University of North Carolina School of Medicine
CDK12 regulates nucleolar organization in cancer cells
Rani George, Harvard Medical School
Principles of epigenetics and chromatin in development and human disease
Ali Shilatifard, Northwestern University
Closing remarks by organizers
Closing networking reception
Thursday agenda
Badge pickup
Opening remarks
Keynote I
Ultra-long-range enhancer–promoter interactions in the Drosophila embryo and brain
Mike Levine, Princeton University
Session I: Transcription factors and enhancers
The tail wagging the dog: Function of the p53 IDR in target gene selection
Peter Verrijzer, Erasmus University Medical Center
Genome-wide relationship of TF binding and the rotational and translational setting of nucleosomes
Frank Pugh, Cornell University
Histone chaperones coupled to DNA replication and transcription control divergent chromatin elements to safeguard cell identity
Reuben Franklin, University of California, Riverside
DNA-guided transcription factor cooperativity shapes face and limb mesenchyme
Seungsoo Kim, Stanford University
Widespread impact of nucleosome remodelers on transcription at cis-regulatory elements
Sarah Hainer, University of Pittsburgh
Unexpected properties and genome-wide functions of DNA sequence-specific transcription factors
Steve Hahn, Fred Hutchinson Cancer Center
Welcome networking reception
Friday agenda
Badge pickup
Session II: Structure and function of transcription complexes
Visualizing the dynamic nature of promoter proximal pausing
Seychelle Vos, Massachusetts Institute of Technology
Structures of mitochondrial transcription initiation machines at work
Quinten Goovaerts, Rega Institute for Medical Research
RNA-mediated regulation of the histone methyltransferase PRC2 involve PRC2 dimerization
Vignesh Kasinath, University of Colorado, Boulder
Widespread epistasis shapes the RNA polymerase II active site
Craig Kaplan, University of Pittsburgh
Integration of pol I and pol III subunit RPAC1 into pol II drives m2,2G mRNA
Xiong Ji, Peking University
Coffee break
Session III: Transcription regulation from 5'-ends to 3'-ends
A conserved interaction between Chd1 and the Paf1 complex controls Chd1 distribution and nucleosome positioning on active genes
Karen Arndt, University of Pittsburgh
Thr4 phosphorylation primes Ser2 phosphorylation on RNA polymerase II and mediates regulation in 3’-end processing
Y. Jessie Zhang, University of Texas at Austin
Coordinate control of the RNA polymerase II transcription cycle by CDK9-dependent, tripartite phosphorylation of SPT5
Robert Fisher, Icahn School of Medicine at Mount Sinai
Regulation of promoter–proximal pause release and transcription elongation
Jesper Svejstrup, University of Copenhagen
KAP1 negatively regulates RNA polymerase II elongation kinetics to activate signal-induced transcription
Iván D'Orso, University of Texas Southwestern Medical Center
Session IV: Chromatin, genome architecture and remodelers
RNA polymerases reshape chromatin architecture and couple transcription on individual fibers
Stirling Churchman, Harvard Medical School
TASOR expression in naive embryonic stem cells safeguards their developmental potential
Laura Banaszynski, University of Texas Southwestern Medical Center
Cohesin mutations expose repressive role of 3D polycomb loops
Oliver Bell, University of Southern California
Regulation of cell identity by 3D super-enhancers
Brian Abraham, St. Jude Children's Research Hospital
SETD2-CDK1 cooperation during G2/M ensures nuclear lamina integrity and genome stability
Brian Strahl, University of North Carolina at Chapel Hill
Chromatin remodeling rewires transcription networks in glioblastoma
Xueqin Sherine Sun, Sanford Burnham Prebys Medical Discovery Institute
Coffee break
Session V: Transcription dynamics, condensates and imaging
ATP-dependent remodeling of chromatin condensates uncovers distinct mesoscale effects of two remodelers
Geeta Narlikar, University of California, San Francisco
Gain-of-function RNA polymerase II partitioning is a shared feature of diverse oncogenic fusions
Heankel Lyons, University of Texas Southwestern Medical Center
Transcriptional activation domains function as amphiphilic hydrophobic-acidic surfactants
Alexandre Erkine, Butler University
Histone acetylation readers Bdf1 and Yaf9 mediate a two-step targeting mechanism of the SWR1 remodeler for H2A.Z deposition at the +1 nucleosome
Anand Ranjan, Johns Hopkins University
The role of histone variants in epigenetic regulation of transcription
Yamini Dalal, National Cancer Institute
Chromatin and nuclear receptor single molecule dynamics and gene regulation in vivo
Diana Stavreva, National Cancer Institute
Explore Alexandria free time
Poster session I
Saturday agenda
Badge pickup
Sunrise session
NSF funding opportunities in molecular and cellular biosciences
Manju Hingorani, National Science Foundation
Session VI: Chromatin, genome architecture and remodelers
Dissection of the molecular architecture and regulatory mechanisms of a robust long-range enhancer at its native locus
John Lis, Cornell University
Enhancer regulation by H3K4me1 methyltransferases
Kai Ge, National Institute of Diabetes and Digestive and Kidney Diseases
CRISPR-engineered mutations and MERFISH single cell spatial transcriptomics reveal the disease mechanism critical for facioscapulohumeral dystrophy
Kyoko Yokomori, University of California, Irvine
Auto-inhibition imposed by a large conformational switch of INO80 regulates nucleosome positioning
Upneet Kaur, University of California, San Francisco
The role of RNA in regulating DNA topological stress intrinsic to RNA polymerase II-dependent transcription RNA
Shannon Lauberth, Northwestern University
Coffee break
Session VII: Transcription dynamics, condensates and imaging
Super-resolution imaging of transcription in living cells
Ibrahim Cissé, Max Planck Institute of Immunobiology and Epigenetics
Scaling laws of human transcriptional activity
Jiayin Hong, University of Cambridge
Single molecule microscopy reveals unexpected features of RNApII transcription
Stephen Buratowski, Harvard Medical School
A real-time in vitro fluorescence transcription assay (RIFT) uncovers basic mechanistic insights about RNA polymerase II activation
Dylan Taatjes, University of Colorado, Boulder
Unraveling crosstalk between histone acetylation and gene activation in living cells
Timothy Stasevich, Colorado State University
Single-molecule imaging studies of chromatin and transcription proteins in live cells and in vitro
Carl Wu, Johns Hopkins University
Free afternoon
Poster session II
Sunday agenda
Badge pickup
Keynote II
The rapidly expanding histone universe
Karolin Luger, University of Colorado, Boulder
Session VIII: Structure and function of transcription complexes
Structural basis of histone mark deposition by SETD2 on upstream nucleosomes
Lucas Farnung, Harvard Medical School
Structure of the Hir histone chaperone complex
Kenji Murakami, University of Pennsylvania
The Cdk8 kinase module of Mediator: When order and disorder go hand in hand
Francois Robert, Institut de Recherches Cliniques de Montreal
Structure of the human CDK8 kinase module and its complex with Mediator
Kuang-Lei Tsai, University of Texas Health Science Center at Houston
Coffee break
Session IX: Transcription, signaling and DNA repair
Molecular and genomic mechanisms of estrogen signaling, enhancer formation and gene regulation
W. Lee Kraus, University of Texas Southwestern Medical Center
Novel interactions within a heterochromatin complex potentiate inter-subunit communication and gene repression
Aaron Johnson, University of Colorado School of Medicine
Understand the dual-role transcription elongation factors in transcription and repair
Dong Wang, University of California, San Diego
Pol II subunit RPB9 interacts with U2AF1 to facilitate exon definition during co-transcriptional pre-mRNA splicing
Xiang-Dong Fu, Westlake University
Session X: Transcription factors and enhancers
The dynamic nature of H3K9me3-heterochromatin in mammalian cells
Ken Zaret, University of Pennsylvania
Mechanism of nucleosome invasion by transcription factors
Lu Bai, Pennsylvania State University
Regulators of pioneer–factor binding and activity
Melissa Harrison, University of Wisconsin–Madison
Development of a standards-driven genomic mapping platform to measure acute Pol II response dynamics
Bryan Venters, EpiCypher Inc.
Transcriptional activation by enhancers
Dan Larson, National Cancer Institute
Coffee break
Session XI: Transcription regulation from 5'-ends to 3'-ends
Co-transcriptional regulation of transient RNA structures by helicases during eukaryotic gene expression
Karla Neugebauer, Yale University
GATO-Seq uncovers RNA polymerase II promoter–proximal pausing dynamics
Roberto Vazquez Nunez, Massachusetts Institute of Technology
Transcription and the mechanism of somatic hypermutation
David Schatz, Yale School of Medicine
Regulation of gene expression and neuronal differentiation by SPOC domain proteins
Dea Slade, Medical University of Vienna
Variation of C-terminal domain governs RNA polymerase II genomic locations and alternative splicing in eukaryotic transcription
Qian Zhang, University of Texas at Austin
Targeting CDK7 function in the RNA polymerase II transcription cycle in inflammatory arthritis
Inez Rogatsky, Weill Cornell Medical College
Poster prize winners & oral presentations
Poster prize sponsored by Epicypher
Closing remarks
Closing networking reception
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