2021 Annual Meeting

Networking events

Interest groups

The goal of these interest groups is to foster communities of people with similar scientific interests to facilitate communication and collaboration. Through two or three hour events, participants can interact, present, discuss and network within a topic-specific community.

Organizers, speakers, panelists and participants must register for the ASBMB Annual Meeting/Experimental Biology 2021 to access these events.


April 26, 2021, 9 a.m. – Noon

Protein interest group — Protein quality control

Chairs: Danish Khan, Stanford University, and Emily Sontag, Marquette University

The goal of this interest group event is to build a community of researchers in the field of protein quality control (PQC). This event will bring together faculty working in the area of PQC and early career researchers including undergraduate and graduate researchers from diverse backgrounds.

Multiple neurodegenerative diseases are linked to protein misfolding caused due to failure of PQC. Understanding the cellular responses to aberrations in PQC is thus an active area of research. Attendees will gain insights about the ‘big questions’ of PQC field and learn about the approaches being taken to understand the basic biology of PQC and PQC-related diseases.

Continue the conversation on the interest group Slack channel: #asbmb-protein-interest-group-


Bede Portz, University of Pennsylvania
Kelly Rainbolt, Stanford University
Eszter Zavodszky, MRC Laboratory of Molecular Biology
Kiersten M. Ruff, Washington University in St. Louis
Rocio Gomez-Pastor, University of Minnesota
Sonya Neal, University of California, San Diego
Darcie Moore, University of Wisconsin
Heeseon An, Memorial Sloan Kettering
April 26, 2021, 10 a.m. – 1 p.m.

Signaling interest group — Cellular communication in health and disease

Chairs: Michelle Mendoza, University of Utah, and Roberto Zoncu, University of California, Berkeley

The goal of this interest group is to build a community of researchers in the field of signaling.

The session will cover current topics and innovative approaches to studying cellular communication, including metabolic signaling, cancer cell signaling and stress response. Special emphasis will be placed on advanced approaches to the study and manipulation of signal transduction, including high-throughput methods, single molecule imaging and quantitative modeling. 

Target audience: Researchers at all levels interested in this topic.

Continue the conversation on the interest group Slack channel: #asbmb-signaling-interest-group


Towards reconstituting the membrane bound mTORC1 signaling system
Yemima Rose Citron, University of California, Berkeley
Reciprocal mechanosignaling between the extracellular matrix and cancer cells in early lung cancer
Rebecca Zitnay, University of Utah
Dynamics and heterogeneity of Erk-induced immediate-early gene expression
Siddhartha (Sidu) Jena, Princeton University
Dynamics of 3D genome organization at single-molecule resolution in living cells
Anders Sejr Hansen, Massachusetts Institute of Technology
Dynamic information exchange between ERK, AKT, mTOR, and AMPK: Quantitative models of metabolic homeostasis and growth control
John Albeck, University of California, Davis
Lacramioara (Lacra) Bintu, Stanford University
Spatiotemporal regulation of AMPK revealed by a sensitive kinase activity reporter
Danielle Schmitt, University of California, San Diego
LiP-MS: A structural proteomics approach for studying pathway activation
Valentina Cappelletti, ETH Zurich
Coordination between fast migrating tumor cells and their microenvironment in mediating melanoma metastasis
Amanpreet Kaur, University of Pennsylvania
Sabrina Spencer, University of Colorado
April 26, 2021, 10 a.m. – Noon

Mitochondria interest group

Chairs: Oleh Khalimonchuk, University of Nebraska–Lincoln, and Laura Lackner, Northwestern University

The goal of this interest group is to build a community for researchers in the field of mitochondria.

This interest group event will promote cross-talk across the areas of basic mitochondrial biology and molecular mechanisms of disease and aging, and provide an opportunity for biomedical researchers to explore and discover potentially unrecognized mechanisms of disease. Holding an interest group meeting that focuses on the diverse aspects of mitochondria and pathways that underlie the pathophysiologic mechanisms of age-associated diseases will provide a forum for uniquely gathering the international community of scientists in mitochondria, cell metabolism, and aging research. 

Target audience: Anyone interested in mitochondrial biology and the multifaceted roles of mitochondria in cellular and systemic physiology.

Continue the conversation on the interest group Slack channel: #asbmb-mitochondria-interest-group-


Molecular mechanisms and functions at mitochondria-lysosome contact sites
Yvette Wong, Northwestern University Feinberg School of Medicine
The role of GTP-dependent assembly in mitofusin-mediated mitochondrial fusion
Suzanne Hoppins, University of Washington
mtFAS: Not just another way to make fatty acids
Sara Nowinski, University of Utah
Spatial organization of assembly of the mitochondria cristae-organizing MICOS complex
Jonathan Friedman, University of Texas Southwestern Medical Center
Translational regulation of yeast mitoribosome biogenesis
Flavia Fontanesi, University of Miami
Loss of OPA-1 in skeletal muscle increases mitochondrial endoplasmic reticulum contact formation
Antentor Hinton, University of Iowa
April 26, 2021, 10 a.m. – Noon

Research education interest group — Collaborative teaching through CURES

Chairs: Ellis Bell, University of San Diego, and Regina Stevens-Truss, Kalamazoo College

The goal of this interest group is to build a community of researchers in the field of collaborative teaching through CURES.

CURES are authentic research experiences incorporated into a regularly scheduled course, making research accessible to all students. They include seven common elements of a research experience: relevance, scientific background, hypothesis development, proposal, experiments (including iteration)/teamwork to explore the hypothesis, data analysis and evidence-based conclusions, and presentation. CURES can be stand-alone or integrated either vertically or horizontally with other courses or institutions to increase emphasis on interdisciplinarity or scientific collaboration, and have been shown to be a high impact teaching practice.

This interest group event will catalyze interdisciplinary discussions around CUREs for teaching undergraduate biology and chemistry — and classes at the interface of these two disciplines, including biochemistry and molecular biology, build community and connect faculty and aspiring faculty with CURE mentors. The focus will be on interinstitutional collaborative CUREs and the key role of student hypothesis development and approaches to build student ownership of the CURE research.

Attendees will learn about the growing community of educators engaging in teaching protocols to increase research based experiences for undergraduate students. In addition, attendees, especially educators from 2-year colleges and postdoctoral fellows, will connect with the newly created CUREs community, OUR CUREs, and experience CURE faculty mentors. 

Target audience: Faculty from diverse institutions (community colleges, PUIs, comprehensive and R1 institutions) interested in learning about course-based undergraduate research (CURE) teaching and postdocs and graduate students interested in teaching paradigms.

Continue the conversation on the interest group Slack channel: #asbmb-research-education-interest-group-


Incorporating your own research into a CURE
Anthony Bell, University of California, San Diego
Starting and developing a CURE in a community college
Tamara Mans, North Hennepin Community College
Towards developing vertically-integrated CUREs at University of Detroit Mercy
Mara Livezey, University of Detroit Mercy
CUREs as a bridge to interdisciplinary collaborations at a PUI
Dwight Williams, Kalamazoo College
April 26, 2021, 10 a.m. – Noon

Structural biology interest group

Chairs: Jennifer Kavran, Johns Hopkins University, and David Taylor, University of Texas at Austin

This interest group is aimed at building a community of researchers in the Structural Biology field.

The program will highlight both emerging areas in structural biology as well as early career scientists covering new techniques including cryo-electron microscopy (cryo-EM), cryo-electron tomography (cryo-ET), and COVID-19 research. In addition, a panel discussion focused on providing resources for trainees (graduate students and postdocs) will be included.

Target audience: Life science researchers and structural biologists of all levels.

Continue the conversation on the interest group Slack channel: #asbmb-structural-biology-interest-group


Replenishing the ends: Structure mechanism of human telomerase
Kelly Nguyen, Medical Research Council Laboratory of Molecular Biology
SARS2 Nsp15 and its search for U
Robin Stanley, National Institute of Environmental and Health Sciences
Rapid structural insights into SARS-CoV-2 S enabled by cryo-EM
Daniel Wrapp, University of Texas, Austin
Endogenous structural biology approaches for challenging systems
Mimi Ho, Columbia University
Cryo-EM structure of the human mRNA translation initiation complex
Jailson Querido, Medical Research Council Laboratory of Molecular Biology
The in situ structure of Parkinson’s disease-linked LRRK2
Elizabeth Villa, University of California, San Diego
April 26, 2021, 11 a.m. – 1 p.m.

Structural biology interest group — Membrane proteins

Chairs: Fran Barrera, University of Tennessee, Knoxville, and Matthias Buck, Case Western Reserve University

The goal of this interest group is to build a community of researchers in the field of structural biology.

The study of membrane proteins is living a golden era, as strides are being made towards understanding how these key proteins function. This networking event will highlight recent advances in a broad range of membrane proteins that are central players in key cellular processes. Topics covered will include cryogenic electron microscopy structures of membrane proteins, particularly receptors and transporters. Other cutting-edge techniques will include several modalities of single-molecule methods. 

Target audience: Researchers interested in biochemistry, biophysics and structural biology.

Continue the conversation on the interest group Slack channel: #asbmb-structural-biology-interest-group


Ras activation in protein condensates
Jay Groves, University of California, Berkeley
Lipid/detergent properties and membrane mimics
Linda Columbus, University of Virginia
Probing the dynamics of lipid-anchored proteins using molecular simulations and experiments
Alex Gorfe, University of Texas Health
Activation mechanisms and biased signaling of the G protein-coupled receptor β2AR
Rajan Lamichhane, University of Tennessee
Protein design reveals roles of transient water wires in proton channel function
Huong Kratochvil, University of California, San Francisco
Gating mechanism in pentameric ligand gated channels: Insights from Cryo-EM
Sudha Chakrapani, Case Western Reserve University
Protein and membrane conformations facilitating virus entry into cells
Lukas Tamm, Virginia University
April 26, 2021, 11 a.m. – 2 p.m.

RNA interest group — RNA virology

Chairs: Blanton Tolbert, Case Western Reserve University, and Sebla Kutluay, Washington University in St. Louis

The goal of this interest group is to build a community of researchers in the field of RNA virology.

This interest group event will bring together scientists who are generally interested in the cellular stages of the replication cycle of RNA viruses but pursue these endeavors using different experimental approaches. The format will encourage cross-talk between those inclined to understand mechanisms by employing structural biochemistry and those individuals who focus more on the cellular stages of molecular virology. Attendees will learn from a group of scientists who approach understanding virus–host pathways from different scientific and technological approaches and the identification of new host-virus pathways to pursue for therapeutic intervention. 

Target audience: Researchers at all career levels.

Continue the conversation on the interest group Slack channel: #asbmb-rna-interest-group


Discovering and modulating RNA regulatory elements within the SARS-CoV-2 and HCV genomes
Anna Marie Pyle, Yale University
Viral RNAs in 3D: Master hijackers of cellular machinery
Jeffrey Kieft, University of Colorado Anshutz Medical Campus
An RNA pseudoknot stimulated HTLV-1 pro-pol programmed -1 ribosomal frameshift
Kathryn Mouzakis, Loyola Marymount University
Establishing a framework to understand mechanisms of action of drugs targeting the picornaviral 2C protein
Calvin Yeager, University of North Carolina at Chapel Hill
Structural modulation of the interaction between EV71 3C protease and stem loop 1D
Christina Haddad, Case Western Reserve University
Generation and function of defective viral genomes during RSV infection
Carolina Lopez, Washington University in St. Louis
RNA modifications at the virus-host interface
Stacy Horner, Duke University
Functional genomics studies of SARS-CoV-2 and three seasonal human coronaviruses
Joseph Luna, Rockefeller University
Translational regulation of HIV-1 and SARS-CoV-2 infections
Maritza Puray-Chavez, Washington University in St. Louis
Elucidating HIV splice variant interactomes using HyPR-MS 
Rachel Knoener, University of Wisconsin–Madison
April 26, 2021, 11 a.m. – 2 p.m.

Neuroscience interest group — Protein function in the nervous system

Chairs: Jason Yi and Harrison Gabel, Washington University in St. Louis

The goal of this interest group is to promote biochemical and molecular biology research in neuroscience and foster communication between mechanistic biochemical researchers and neuroscientists throughout the global research community.

The session will explore how a basic, mechanistic understanding of proteins can translate into new insights into nervous system function, disease, and evolution. The talks in this interest group will emphasize studies that perform mechanistic analyses of single proteins and enzymes in the context of nervous system function, and in particular, how these studies provide new insights into neurological disorders and potential treatments.

This interest group will provide an opportunity for trainees to network with researchers outside their current fields to facilitate career development.

Target audience: Molecular neuroscientists and those interested in learning more about neuroscience research.

Continue the conversation on the interest group Slack channel: #asbmb-neuroscience-interest-group


Angela Mabb, Georgia State University
Jiami Guo, University of Calgary
Victor Anggono, Queensland Brain Institute
Shigeki Iwase, University of Michigan
Harrison Gabel, Washington University in St. Louis
Jason Yi, Washington University in St. Louis
April 26, 2021, 1 p.m. – 4 p.m.

Glycobiology interest group

Chairs: Amanda Lewis, University of California, San Diego Health, and Nadine Samara, National Institutes of Health

This interest group is aimed at building a community of researchers in the field of glycobiology.

The program will include discussions addressing problems associated with a lack of diversity, equity and inclusion in science, and glycoscience in particular; provide mental health advice/resources; and cover cutting-edge research in the field. Attendees will engage in discussions following the scientific talks and learn about the career path of a prominent glycobiologist at the FDA, Dr. Willie Vann.

Target audience: Researchers in glycosciences at all levels, leaders interested in building equity, diversity and inclusion in the glycosciences and early career researchers interested in learning strategies to manage mental health challenges.

Continue the conversation on the interest group Slack channel: #asbmb-glycobiology-interest-group


Developing microbiome-directed foods: A journey from gnotobiotic mouse models to humans
Omar Delannoy-Bruno, Washington University in St. Louis School of Medicine
Sialidases and sialoglycan foraging in dysbiotic vaginal microbiota
Kavita Agarwal, University of California, San Diego
Improved glycopeptide identification using high-field asymmetric waveform mobility spectrometry (FAIMS)
Kathirvel Alagesan, Max Planck Institute
O-GlcNAcylation in the pituitary gland: From development to endocrine function
Stephanie Olivier-Van Stichelen, Medical College of Wisconsin
The Acinetobacter glycoprotease CpaA, a new component of the glycoproteomics toolbox
Mario Feldman, Washington University in St. Louis
Following a sweet trail – My career path at FDA
Willie Vann, United States Food and Drug Administration
Wellness & resilience – Underappreciated skills for scientists
Sharon Milgram, National Institutes of Health
Strategies to combat bias and discrimination in STEM
Lisa Willis, University of Alberta
April 26, 2021, 1 p.m. – 3 p.m.

Lipid Research Division interest group — Lipid and membrane biochemistry

Chairs: John Burke, University of Victoria, and Mike Airola, Stony Brook Medicine

The goal of this interest group is to continue to engage the lipid community.

Attendees will learn about exciting lipid and membrane research.

Target audience: Biochemists and biologists who are interested in lipid and membrane research.

Continue the conversation on the interest group Slack channel: #asbmb-lipid-research-division-interest-group


Phosphorylation switches on inter-organelle contacts and lipid transport
Fabien Alpy, Institute of Genetics and Molecular and Cellular Biology
Structure and mechanism of TRAPPIII-mediated Rab1 activation
Aaron Joiner, Cornell University
The C-terminal regulatory motif in PI3Kgamma and its implications in disease and inhibition
Manoj Rathinaswamy, University of Victoria
Filovirus matrix protein VP40 displays lipid-specific behavior and oligomerization that go beyond the lipid headgroup
Souad Amiar, Purdue University
April 26, 2021, 1 p.m. – 3 p.m.

Enzymology interest group

Chairs: Kayunta Johnson-Winters, University of Texas at Arlington, and Juan Mendoza, University of Chicago

The goal of this interest group is to build a community of researchers in the field of enzymology.

This interest group event will provide an in-depth and multi-level view of how the structural studies of enzymes elucidate essential cellular functions. The enzymes covered are important at the inner core of a cell through the cell's surface such as cell surface receptors. The research to be presented will be focused on the structure-function of enzymes essential to cellular function, cellular regulation, and relevant to human health and disease. Techniques and cutting-edge research include X-ray crystallography, cryo-EM, NMR, enzyme kinetics, enzymology, and protein engineering.

Attendees will be exposed to a diverse panel of researchers performing cutting-edge science and gain insights into how some scientists use combined structure and engineering approaches to elucidate key enzymatic processes of cells. New investigators will also leave with insight related to their careers and respective fields through a Q&A session related to research, diversity, inclusion and promotion.

Target audience: researchers at all career levels with an interest in structure, enzymology, and human health and disease.

Continue the conversation on the interest group Slack channel: #asbmb-enzymology-interest-group


Tunnels for lipid transport across the bacterial cell envelope
Gira Bhabha, New York University School of Medicine Skirball Institute
A kinase-dependent phosphoswitch controls human circadian timekeeping
Carrie Partch, University of California, Santa Cruz
Seeing red – a cytochrome c is the natural electron acceptor for nicotine oxidoreductase
Frederick Stull, Western Michigan University
Control of protein function by assembly: implications for stress response
Breann L. Brown, Vanderbilt University School of Medicine
April 26, 2021, 1 p.m. – 3 p.m.

Signaling interest group — Nuclear receptors

Chairs: Rebecca Riggins, Georgetown University, and Douglas Kojetin, Scripps Research Institute

This interest group is intended to bring together members of the scientific community who study nuclear receptors, which are critically important players in normal and disease physiology.

Nuclear receptors with well-established connections to specific diseases (e.g. the estrogen and androgen receptors in breast and prostate cancer, respectively) are often highlighted in spotlight sessions at major meetings, or the subjects of entirely independent conferences. However, the nuclear receptor field as a whole lacks a meeting venue that allows the cross-pollination of innovative ideas and conceptual advances drawn from the study of the lesser-known orphan nuclear receptors to these steroid hormone receptors, and back again.

Attendees will be able to connect with each other during the interest group event and throughout the main ASBMB meeting, with the idea that this will nucleate longer-term networking and collaborative opportunities.

Target audience: Researchers at all career levels who are already active in the nuclear receptor field, and those who are interested in moving towards this research area.

Continue the conversation on the interest group Slack channel: #asbmb-signaling-interest-group


Hormone receptor 4 is required in muscles and distinct ovarian cell types to regulate specific steps of Drosophila oogenesis
Lesley N. Weaver, Indiana University
Insane in the membrane: The role of membrane steroid receptors in embryonic development
Daniel A. Gorelick, Baylor College of Medicine
Artifacts, crystals, and other treasures: A quest for the structural basis of heme-dependent REV-ERBbeta activity
Sarah A. Mosure, Scripps Institute, Florida
Discovery of oleic acid as an endogenous ligand of TLX/Nr2E1 and a biomarker of neurogenesis
Miriana Maletic-Savatic, Baylor College of Medicine
Dynamic regulation of ligand-activated transcriptional programs and chromatin architecture by nuclear receptor condensates
Sreejith J. Nair, University of California, San Diego
April 26, 2021, 2 p.m. – 5 p.m.

Chemical biology interest group

Chairs: Minkui Luo, Memorial Sloan Kettering Cancer Center, and Jianmin Gao, Boston College

This interest group is aimed at building a community of researchers in the field of chemical biology.

This interest group is assembled for collaborative, synergistic interaction of attendees with significant portion of the program for underrepresented, junior-level faculty members. This interest group can be of a great platform for ASBMB biologists to be exposed to emerging chemical biology tools, technology and methods. There are also existing chemical biology challenges that ASBMB biologists can collaboratively address with the aim for a group of core participants to potentially establish an annual meeting program. The ultimate goal is to inspire chemical biologists to mingle with the ASBMB community for mutual benefits: the utility of chemical tools to interrogate challenging biology and the advancement of novel biological discovery with chemical tools.

Target audience: Chemist biologists (likely first-time ASBMB attendees) with interest in searching for biological questions; the current ASBMB members with interest in chemical biology to develop tools or solve their existing problem.

Continue the conversation on the interest group Slack channel: #asbmb-chemical-biology-interest-group


Raymond Moellering, University of Chicago
Uncovering cancer-associated epigenetic events using novel chemical tools
Yael David, Memorial Sloan Kettering Cancer Center
Directed evolution of reverse transcriptases to study epitranscriptomics and RNA biology
Huiqing (Jane) Zhou, Boston College
Single-molecule studies of genetic and epigenetic machinery
Shixin Liu, Rockefeller University
Chemical biology of protein aggregation in membraneless organelles and the stressed proteome
Xin Zhang, Pennsylvania State University
Chemical tools that IMPACT lipid signaling
Jeremy Baskin, Cornell University
Methods to monitor an increase in proteasome activity in live cells
Darci Trader, Purdue University
April 26, 2021, 2 p.m. – 5 p.m.

Protein interest group — Post-translational modifications

Chairs: Lauren Ball, Medical University of South Carolina, and Fangliang Zhang, University of Miami Miller School of Medicine

The goal of this interest group is to provide a forum enabling interaction of scientists interested in the elucidating the impact of regulatory post-translational modifications on physiology, disease and drug response.

Novel approaches for enrichment and detection of PTMs including (nanopore, antibody) and detection methodology (mass spectrometry) and introduction to less well explored PTMs (examples: non-acetyl acylation, sulfation, arginylation) and their relevance to physiology and disease will be covered.

Target audience: Research scientists, physicians, postdoctoral fellows, graduate and undergraduate students.

Continue the conversation on the interest group Slack channel: #asbmb-protein-interest-group-


Nanopores for single molecule protein sequencing and PTM detection
Aleksei Aksimentiev, University of Illinois Urbana-Champaign
Pathological variation of collagen proline hydroxylation in the tumor microenvironment detected by imaging mass spectrometry
Peggi Angel, Medical University of South Carolina
Modulation of innate immunity by succination
Kate A. Fitzgerald, University of Massachusetts Medical School
Role of arginine methyltransferase 5 in AKT signaling
Wenjian Gan, Medical University of South Carolina
Ubiquitination modulates protein energetics and degradation kinetics in a site-specific manner
Andreas Martin, University of California, Berkeley
A new strategy for the enrichment and quantitation of native O-GlcNAc modified peptides from cells and tissues
Sam Myers, La Jolla Institute for Immunology
BOOSTing quantitative phosphotyrosine proteomics and beyond
Arthur Salomon, Brown University
Protein arginylation: An ancient and conserved oxygen sensing mechanism
Fangliang Zhang, University of Miami Miller School of Medicine
April 26, 2021, 3 p.m. – 5 p.m.

Signaling interest group — Triple negative breast and ovarian cancers

Chairs: Marina Holz, New York Medical College, and Mythreye Karthikeyan, University of Alabama at Birmingham

This interest group is aimed at building a community of researchers in the field of signaling–cancers.

The program will cover engaging talks on current topics and innovative approaches to study cellular communication, including metabolic signaling, cancer cell signaling and stress response. Special emphasis will be on advanced approaches to study and manipulate signal transduction, including high-throughput methods, single molecule imaging, and quantitative modeling. Attendees will be exposed to the most recent developments in the field and will have an opportunity to interact with speakers and with each other.

Target audience: Researchers at all career stages interested in the topic.

Continue the conversation on the interest group Slack channel: #asbmb-signaling-interest-group


Alternative transcription factor targets for high grade serous cancer and TNBC other than ER/PR
Joanna E. Burdette, University of Illinois
Plasticity of telomere maintenance mechanisms during mammary tumorigenesis
William P. Schiemann, Case Western Reserve University
TNBC and serous ovarian cancers co-opt a program of immune suppression utilized by fetal trophoblasts
Jennifer K. Richer, University of Colorado
Comparison of ovarian cancer and triple-negative breast cancer tumors at the signaling level using multi-omics data
Jason McDermott, Pacific Northwest National Laboratory