|Elizabeth Rhoades, Yale Univ.
||Scott Showalter, The Pennsylvania State Univ.
This theme is made up of four symposia, one scheduled each
day of the meeting, Sun – Wed. Please
read below for invited speaker and session schedule information. In addition to the invited talks listed
below, short talks will be selected from the submitted abstracts. To be considered for a volunteered talk in
this theme, submit your abstract to an ASBMB topic category number: 2090-2108,
by the November 6th submission deadline. All volunteered abstracts will be programmed
for poster presentation. Those selected
for oral presentation will also present a poster. Programming notifications will be sent in
mid-January. We look forward to seeing
you at the Boston Convention and Exhibition Center, BCEC, March 28 – April 1,
Mediating Protein Interactions: Is Folding Required?
Sunday, March 29, 2015, 3:55 PM - 6:10 PM
Session Chair: Elizabeth Rhoades, Yale Univ.
Jane Clark, Univ. of Cambridge
Mechanisms of folding upon binding
Ashok Deniz, The Scripps Res. Inst.
Allostery modulation by protein intrinsic disorder at single molecule
Tanja Mittag, St. Jude Children's Res. Hosp.
The role of substrate disorder and multivalency in regulating ubiquitination
Regulating Functional Interactions by Dysfunctional Proteins
Monday, March 30, 2015, 9:45 AM - 12:00 PM
Session Chair: Carlos Camacho, Univ. of Pittsburgh
David Eliezer, Weill Cornell Med. Col.
Structural biology of tau and alpha-synuclein
Elizabeth Rhoades, Yale Univ.
Determining a functional mechanism of a dysfunctional protein
Collin Stultz, MIT
The mechanism of amyloid beta fiber elongation
Defining Protein Disorder
Tuesday, March 31, 2015, 3:55 PM - 6:10 PM
Session Chair: Steve Metallo, Georgetown Univ.
Mónika Fuxreiter, Univ. of Debrecen
Fuzziness imparts versatility on signaling
Jörg Gsponer, Univ. of
Promiscuous but still selective in partner selection
Scott A. Showalter, The Pennsylvania State Univ.
Assessing Intrinsically Disordered Protein Structure and Function through
Carbon Detected NMR
Targeting Disorder with Small Molecules
Wednesday, April 1, 2015, 9:00 AM - 11:15 AM
Session Chair: Scott Showalter, The Pennsylvania State Univ.
Carlos J. Camacho, Univ. of Pittsburgh
Modulating the regulatory role of disordered proteins using small molecules
Steven J. Metallo, Georgetown Univ.
Specificity and Promiscuity in Small Molecule Binding to Intrinsically
Disordered Protein Regions
Radford, Univ. of Leeds
Biophysical studies of amyloid formation mechanisms