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When oncogenes collide in brain development
Researchers at University Medical Center Hamburg, found that elevated oncoprotein levels within the Wnt pathway can disrupt the brain cell extracellular matrix, suggesting a new role for LIN28A in brain development.
The data that did not fit
Brent Stockwell’s perseverance and work on the small molecule erastin led to the identification of ferroptosis, a regulated form of cell death with implications for cancer, neurodegeneration and infection.
Building a career in nutrition across continents
Driven by past women in science, Kazi Sarjana Safain left Bangladesh and pursued a scientific career in the U.S.
Avoiding common figure errors in manuscript submissions
The three figure issues most often flagged during JBC’s data integrity review are background signal errors, image reuse and undeclared splicing errors. Learn how to avoid these and prevent mistakes that could impede publication.
Ragweed compound thwarts aggressive bladder and breast cancers
Scientists from the University of Michigan reveal the mechanism of action of ambrosin, a compound from ragweed, selectively attacks advanced bladder and breast cancer cells in cell-based models, highlighting its potential to treat advanced tumors.
Lipid-lowering therapies could help treat IBD
Genetic evidence shows that drugs that reduce cholesterol or triglyceride levels can either raise or lower inflammatory bowel disease risk by altering gut microbes and immune signaling.
Key regulator of cholesterol protects against Alzheimer’s disease
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From humble beginnings to unlocking lysosomal secrets
Monther Abu–Remaileh will receive the ASBMB’s 2026 Walter A. Shaw Young Investigator Award in Lipid Research at the ASBMB Annual Meeting, March 7-10 in Washington, D.C.
Chemistry meets biology to thwart parasites
Margaret Phillips will receive the Alice and C. C. Wang Award in Molecular Parasitology at the ASBMB Annual Meeting, March 7-10 in Washington, D.C.
ASBMB announces 2026 JBC/Tabor awardees
The seven awardees are first authors of outstanding papers published in 2025 in the Journal of Biological Chemistry.
Missing lipid shrinks heart and lowers exercise capacity
Researchers uncovered the essential role of PLAAT1 in maintaining heart cardiolipin, mitochondrial function and energy metabolism, linking this enzyme to exercise capacity and potential cardiovascular disease pathways.
Decoding how bacteria flip host’s molecular switches
Kim Orth will receive the Earl and Thressa Stadtman Distinguished Scientists Award at the ASBMB Annual Meeting, March 7–10, just outside of Washington, D.C.
Defining JNKs: Targets for drug discovery
Roger Davis will receive the Bert and Natalie Vallee Award in Biomedical Science at the ASBMB Annual Meeting, March 7–10, just outside of Washington, D.C.
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